Evidence map›Paper›PMID 40300167›Full record

ArticleJMIR research protocols2025

Prognostic Disclosure in Metastatic Breast Cancer: Protocol for a Scoping Review.

Linda Battistuzzi, Irene Giannubilo, Claudia Bighin

Abstract read
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Linda BattistuzziUnit of Medical Oncology 2, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID 0000-0003-2340-3059
Irene GiannubiloUnit of Medical Oncology 2, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID 0009-0009-2377-2699
Claudia BighinUnit of Medical Oncology 2, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID 0000-0001-9956-0216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrognostic disclosure enables shared decision-making by keeping patients informed about their health and involved in treatment-related choices. In metastatic cancer, patients who understand their prognosis are better placed to evaluate their health situation, have more realistic expectations about treatment, and better end-of-life (EoL) care. However, many oncologists feel uncomfortable discussing prognoses with their patients, as they worry about causing psychological distress and diminishing hope. Other barriers to prognostic disclosure are associated with the inherent uncertainty of prognostication, which is especially prominent in metastatic breast cancer (mBC), as are a lack of timely discussions about EoL care and poor quality of care at EoL. Despite this background, a preliminary literature search has shown that, to date, knowledge about prognostic disclosure in mBC has not been systematically mapped.

objectiveThe overall aim of this scoping review will be to comprehensively explore the existing literature pertaining to prognostic disclosure in mBC.

methodsThis scoping review will follow Arksey and O'Malley's expanded framework. We will systematically search electronic databases for peer-reviewed, published journal articles to identify appropriate studies. First, 2 members of the research team will independently review titles and abstracts. Then, they will review full texts to establish whether articles meet inclusion criteria. A data chart for collecting and sorting information will be developed. Results will be reported following the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines and summarized quantitatively and qualitatively.

resultsWe expect to present the results in a scoping review in 2025.

conclusionsTo our knowledge, this scoping review will be the first systematic effort aimed at mapping existing literature on prognostic disclosure in mBC, in which rapidly developing therapeutic approaches and changing disease trajectories generate new uncertainties and place new communicative demands on oncologists. The insights gained from this scoping review will inform the development of an interview schedule with oncologists, oncology residents, oncology nurses, and patients with mBC to explore their experiences, views, and perceptions about prognostic disclosure. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/57256.

Indexed as

Breast NeoplasmsDisclosureTruth DisclosureFemaleHumansNeoplasm MetastasisPhysician-Patient RelationsPrognosisResearch DesignScoping Reviews as TopicTerminal Careadvanced breast cancercommunicationethicsmetastatic breast cancerprognosisprognostic disclosureprotocolscoping reviewshared decision-makingtruth-telling

Identifiers

PMID40300167
PMCPMC12076028

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.