Evidence map›Paper›PMID 40300009›Full record

ArticlePLOS global public health2025

Gaps in hypertension and diabetes treatment among people living with and without HIV: Findings from a prospective cohort study in Kenya, Nigeria, Tanzania, and Uganda, 2013-2023.

Matthew L Romo, Nicole Dear, Trevor A Crowell, Seth Frndak, Ajay P Parikh, Hannah Kibuuka, John Owuoth, Valentine Sing'oei, Jonah Maswai, Emmanuel Bahemana and 6 more

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Matthew L RomoU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.ORCID https://orcid.org/0000-0002-3038-0644
Nicole DearU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.ORCID https://orcid.org/0000-0002-8026-9901
Trevor A CrowellU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.ORCID https://orcid.org/0000-0001-5947-265X
Seth FrndakU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.ORCID https://orcid.org/0000-0002-2049-2204
Ajay P ParikhU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Hannah KibuukaMakerere University Walter Reed Project, Kampala, Uganda.
John OwuothU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Kisumu, Kenya.
Valentine Sing'oeiU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Kisumu, Kenya.ORCID https://orcid.org/0000-0001-9434-9630
Jonah MaswaiU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Kericho, Kenya.
Emmanuel BahemanaU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Mbeya, Tanzania.
Victor AnyebeU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Abuja, Nigeria.
Zahra ParkerHenry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, United States of America.
Julie A AkeU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
J Sean CavanaughU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Neha ShahU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.ORCID https://orcid.org/0000-0002-9575-9161
African Cohort Study (AFRICOS) Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension and diabetes are increasingly important contributors to morbidity and mortality in African countries, including among people living with HIV (PLWH) who are on lifelong antiretroviral therapy. However, local HIV care programs have historically not included management of noncommunicable diseases. The African Cohort Study enrolls PLWH and people living without HIV (PLWoH) aged 15 years and older who are receiving clinical care at 12 PEPFAR-supported health facilities in Kenya, Nigeria, Tanzania, and Uganda. Participants undergo clinical assessments and medical record review every six months. We defined hypertension as a persistently elevated systolic and/or diastolic blood pressure ≥140/90 mmHg at two consecutive 6-monthly visits or receipt of hypertension medication. We defined diabetes as a single study visit with a fasting plasma glucose ≥7.0 mmol/L and/or non-fasting plasma glucose ≥11.1 mmol/L or receipt of diabetes medication. We computed descriptive statistics for hypertension/diabetes prevalence and treatment and used random intercept models adjusted for demographic and clinical characteristics to examine predictors of untreated hypertension and diabetes. From 2013 through 2023, among 3617 participants, 692 (19.1%) met our definition of hypertension, with a prevalence of 19.5% among PLWH and 17.3% among PLWoH; 276 (39.9%) received hypertension treatment. No significant difference in untreated hypertension was found comparing PLWH with PLWoH (adjusted risk ratio [aRR] 0.93, 95% confidence interval [CI]: 0.84-1.04). Among 3995 participants, 253 (6.3%) met our definition of diabetes, with a prevalence of 6.6% among PLWH and 4.7% among PLWoH; 51 (20.2%) received diabetes treatment. No significant difference in untreated diabetes was found comparing PLWH with PLWoH (aRR 1.01, 95% CI: 0.91-1.12). The high burden of untreated hypertension and diabetes among PLWH and PLWoH highlight the need for integrated non-communicable disease management within existing HIV services and strengthening of primary healthcare systems.

Identifiers

PMID40300009
PMCPMC12040259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.