Evidence map›Paper›PMID 40299787›Full record

ArticleDrug and alcohol review2025

Age, period and cohort trends in hospital admissions for alcohol-related liver disease in Australia, 1993-2020.

Michael Livingston, Will Gilmore, Nic Taylor, Tanya Chikritzhs, Wing See Yuen, Jessica Howell, Ericka Flores, Michael Curtis, Paul Dietze

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Michael LivingstonNational Drug Research Institute, enAble Institute, Faculty of Health Sciences, Curtin University, Melbourne, Australia.ORCID 0000-0002-8995-9386
Will GilmoreNational Drug Research Institute, enAble Institute, Faculty of Health Sciences, Curtin University, Melbourne, Australia.
Nic TaylorNational Drug Research Institute, enAble Institute, Faculty of Health Sciences, Curtin University, Melbourne, Australia.ORCID 0000-0002-8700-5909
Tanya ChikritzhsNational Drug Research Institute, enAble Institute, Faculty of Health Sciences, Curtin University, Melbourne, Australia.ORCID 0000-0001-8871-3205
Wing See YuenNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0002-2791-6858
Jessica HowellThe Burnet Institute, Melbourne, Australia.
Ericka FloresSt Vincent's Hospital Melbourne, Melbourne, Australia.
Michael CurtisNational Drug Research Institute, enAble Institute, Faculty of Health Sciences, Curtin University, Melbourne, Australia.ORCID 0000-0002-1814-0867
Paul DietzeNational Drug Research Institute, enAble Institute, Faculty of Health Sciences, Curtin University, Melbourne, Australia.ORCID 0000-0001-7871-6234

Funding

Australian GovernmentAustralian Research Council FT210100656Curtin University, Western Australia
6 · The paper itself

Abstract

introductionThis study examines trends in admissions for alcohol-related liver disease (ALD) for Australian men and women between 1993 and 2020 and disaggregates these trends into age, period and cohort components.

methodRetrospective age-period-cohort analysis of hospital admissions with a primary diagnosis of ALD.

settingAustralia. CASES: 133,705 hospital admissions - 97,755 men (73%); 35,950 women (27%). MEASUREMENTS: Hospital admissions for ALD were grouped into five-year age groups (15-19, 20-24 up to 85 and over) for each financial year between 1992/93 and 2020/21.

resultsALD admission rates were substantially higher for men than women. Rates for men increased up to 2005 and subsequently declined before an uptick in 2020. For women, rates increased steadily over the period. In age-period-cohort models, male admission rates were relatively stable over both period and cohort. For women, period effects increased steadily - compared to the period reference year of 2006, the RR for women's admission rates was 0.69 (0.65, 0.74) in 1993, increasing to 1.23 (1.18, 1.29) in 2020. Recent cohorts had significantly higher rates of hospital admission for ALD than those born earlier (e.g., women born in the 1996 cohort had an RR of 2.2 (1.8, 2.7) relative to those born in the reference year 1956). DISCUSSION AND

conclusionsIncreases in hospital admissions for ALD, especially since the COVID-19 pandemic, point to the need for effective identification and interventions for people with alcohol-use disorders at risk of chronic disease outcomes.

Indexed as

HospitalizationLiver Diseases, AlcoholicAdolescentAdultAgedAged, 80 and overAge FactorsAustraliaCohort StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesSex FactorsYoung Adultalcoholcohortliver diseasemorbiditytrends

Identifiers

PMID40299787
PMCPMC12117307

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