ArticleAngewandte Chemie (International ed. in English)2025
Chemically Fueled Active Transport.
Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Temporal dependence emerges from a carbodiimide driven acid-anhydride equilibrium coupled to a photocatalytic decarboxylation reaction.Chemical science · 2026Article
- Transient Activation Windows Program Adaptive Photochemical Responses.Angewandte Chemie (International ed. in English) · 2026Article
- Recent Advancements in Information Ratchet Design.Molecules (Basel, Switzerland) · 2026Review
- A Versatile Strategy for Light-Driven Active Transport of Ions.Angewandte Chemie (International ed. in English) · 2026Article
- Chemically Fueled, Active Droplets Prevent the Aging of Peptides into Amyloid-Like Fibers.Journal of the American Chemical Society · 2025Article
- Active Transport of Macrocycles into Micelles Using Molecular Pumps.Angewandte Chemie (International ed. in English) · 2025Article
- Interfacial effects determine nonequilibrium phase behaviors in chemically driven fluids.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Chemically Fueled Active Transport.Angewandte Chemie (International ed. in English) · 2025Article
- Catalysis-driven Active Transport Across a Liquid Membrane.Angewandte Chemie (International ed. in English) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Biology uses chemical potential differences from molecules like ATP to drive membrane pumps, transporting molecules across membranes even against concentration gradients. Here, we report a synthetic system that transports small molecules from an aqueous phase (the sender) to an aqueous receiver across a centimeter-sized immiscible solvent at the expense of chemical energy. Molecules with high chemical potential (fuels) in the sender phase transiently activate the transporter molecules, which enter the immiscible solvent and exit on the receiver phase side, thus allowing transport from sender to receiver against a concentration gradient. Importantly, we show this active transport mechanism transports molecules across a hydrophobic barrier without complex pumping machinery. Using a reaction-diffusion model, we identify the critical parameters that determine the efficiency of active transport. Selective transport enables the sorting of a mixture of different molecules. In future work, we will use these design criteria to actively transport molecules across membranes, e.g., of vesicles, at the expense of chemical fuel, thereby mimicking biological processes and enabling the feeding of synthetic cells.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.