Evidence map›Paper›PMID 40299698›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Distantly related bacteria share a rigid proteome allocation strategy with flexible enzyme kinetics.

Manlu Zhu, Matteo Mori, Terence Hwa, Xiongfeng Dai

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Metabolic engineering ofSynthetic and systems biotechnology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Heterologous expression ofEngineering microbiology · 2026
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manlu Zhu *State Key Laboratory of Green Pesticides, Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, Department of Microbiology, School of Life Sciences, Central China Normal University, Wuhan 430079, China.ORCID 0000-0003-0225-5704
Matteo Mori *Department of Physics, University of California, San Diego, La Jolla, CA 92093-0319.ORCID 0000-0002-6263-8021
Terence HwaDepartment of Physics, University of California, San Diego, La Jolla, CA 92093-0319.ORCID 0000-0003-1837-6842
Xiongfeng DaiState Key Laboratory of Green Pesticides, Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, Department of Microbiology, School of Life Sciences, Central China Normal University, Wuhan 430079, China.ORCID 0000-0002-8225-1799

Funding

Quantitative Systemic Studies of Bacterial PhysiologyR35GM152133 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TERENCE HWA · 2024 to 2026
$1.8M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM152133Human Frontier Science Program (HFSP) RGP013/2024MOST | National Natural Science Foundation of China (NSFC) 2022YFF1000400MOST | National Natural Science Foundation of China (NSFC) 32270034MOST | National Natural Science Foundation of China (NSFC) 32370044MOST | National Natural Science Foundation of China (NSFC) 32470038NIGMS NIH HHS R35 GM152133| Science Fund for Distinguished Young Scholars of Hubei Province () 2022CFA044Simons Foundation (SF) 542387
6 · The paper itself

Abstract

Bacteria are known to allocate their proteomes according to how fast they grow, and the allocation strategies employed strongly affect bacterial adaptation to different environments. Much of what is currently known about proteome allocation is based on extensive studies of the model organism

Indexed as

Bacterial ProteinsProteomeVibrioEscherichia coliKineticsSpecies SpecificityBacterial ProteinsProteomebacterial growthbacterial phylogenyenzyme kineticsproteomicsresource allocation

Identifiers

PMID40299698
PMCPMC12067254

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.