Evidence map›Paper›PMID 40299675›Full record

ArticleBiomedicines2025

Druggability Studies of Benzene Sulfonamide Substituted Diarylamide (E3) as a Novel Diuretic.

Hang Zhang, Shuyuan Wang, Nannan Li, Yue Xu, Zhizhen Huang, Yukun Zhang, Jing Li, Yinglin Zuo, Min Li, Runtao Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hang ZhangDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.ORCID 0009-0006-0307-8622
Shuyuan WangDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Nannan LiDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Yue XuDivision of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-2755-4719
Zhizhen HuangDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Yukun ZhangChongqing Key Laboratory of Development and Utilization of Genuine Medicinal Materials in Three Gorges Reservoir Area, Chongqing 404120, China.
Jing LiThe State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd., Dongguan 523871, China.
Yinglin ZuoThe State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd., Dongguan 523871, China.
Min LiDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.ORCID 0000-0003-2796-294X
Runtao LiSchool of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Baoxue YangDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.ORCID 0000-0002-7966-2095

Funding

Beijing Natural Science Foundation 7212151National Natural Science Foundation of China 81974083National Natural Science Foundation of China 82273999the grant from the non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2022-JKCS-15
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

diuretichyponatremiapharmacokineticsafety evaluationstructure optimizationurea transporter inhibitor

Identifiers

PMID40299675
PMCPMC12024912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.