Evidence map›Paper›PMID 40299554›Full record

ArticleBiomedicines2025

A 23-Plex Cytokine/Chemokine Analysis Identifies TNFRII, MMP-8, and sIL-1RII as Potential Biomarkers for Systemic Sclerosis.

Carlo Perricone, Giacomo Cafaro, Roberto Dal Pozzolo, Lorenza Bruno, Nicole Sasso, Roberta Cecchetti, Matteo Antonucci, Fabiana Topini, Onelia Bistoni, Patrizia Mecocci and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carlo PerriconeSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.ORCID 0000-0003-4771-6981
Giacomo CafaroSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.ORCID 0000-0003-1774-1916
Roberto Dal PozzoloSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.ORCID 0009-0004-2157-4908
Lorenza BrunoSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.
Nicole SassoSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.
Roberta CecchettiSection of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.
Matteo AntonucciSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.
Fabiana TopiniSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.
Onelia BistoniSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.
Patrizia MecocciSection of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.ORCID 0000-0003-0729-5246
Roberto GerliSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.
Elena BartoloniSection of Rheumatology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.ORCID 0000-0003-4776-2136

Funding

University of Perugia Progetto Ateneo 2021
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkerscytokinesIL-1RIIMMP-8systemic sclerosisTNFRII

Identifiers

PMID40299554
PMCPMC12025288

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.