Evidence map›Paper›PMID 40299449›Full record

ArticleBiomedicines2025

Metabolic Alterations in Women with Lipedema Compared to Women with Lifestyle-Induced Overweight/Obesity.

Małgorzata Jeziorek, Maciej Wuczyński, Monika Sowicz, Agnieszka Adaszyńska, Andrzej Szuba, Angelika Chachaj

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Vascular changes and their implications in lipedema.Frontiers in cell and developmental biology · 2026
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Małgorzata JeziorekDepartment of Dietetics and Bromatology, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Maciej WuczyńskiStatistical Analysis Centre, Wroclaw Medical University, 50-372 Wroclaw, Poland.
Monika SowiczDepartment of Angiology and Internal Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Agnieszka AdaszyńskaDepartment of Angiology and Internal Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Andrzej SzubaDepartment of Angiology and Internal Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Angelika ChachajDepartment of Angiology and Internal Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLipedema is a chronic disorder characterized by disproportionate fat accumulation in the extremities, predominantly affecting women. Unlike obesity, lipedema might be associated with a lower prevalence of metabolic alterations despite often coexisting with overweight or obesity. Fat distribution plays a crucial role in metabolic differences, with gynoid fat in lipedema being associated with a lower risk of insulin resistance and cardiovascular disease. The present study aims to compare biochemical parameters between women with lipedema and those with lifestyle-induced overweight/obesity.

Indexed as

fat distributionlipedemametabolic alterationsoverweight/obesity

Identifiers

PMID40299449
PMCPMC12024828

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.