Evidence map›Paper›PMID 40299419›Full record

ReviewBiomedicines2025

Using Artificial Intelligence to Enhance Myelodysplastic Syndrome Diagnosis, Prognosis, and Treatment.

Fabio Stagno, Giuseppe Mirabile, Patricia Rizzotti, Adele Bottaro, Antonio Pagana, Sebastiano Gangemi, Alessandro Allegra

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fabio StagnoDivision of Hematology, AOU Policlinico "G. Martino", Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy.ORCID 0000-0002-7947-158X
Giuseppe MirabileDivision of Hematology, AOU Policlinico "G. Martino", Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy.
Patricia RizzottiDivision of Hematology, AOU Policlinico "G. Martino", Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy.
Adele BottaroDivision of Hematology, AOU Policlinico "G. Martino", Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy.
Antonio PaganaDivision of Hematology, AOU Policlinico "G. Martino", Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy.
Sebastiano GangemiAllergy and Clinical Immunology Unit, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria, 98125 Messina, Italy.
Alessandro AllegraDivision of Hematology, AOU Policlinico "G. Martino", Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy.ORCID 0000-0001-6156-8239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelodysplastic syndromes represent a group of hematological neoplastic diseases caused by defective stem cells causing cytopenia and abnormal hematopoiesis. More than 30% of myelodysplastic syndrome cases develop into acute myeloid leukemia. An analysis of bone marrow samples, peripheral blood smears, multiparametric flow cytometry data, and clinical patient information is part of the current, time-consuming, and labor-intensive work up for myelodysplastic syndromes. Nowadays, clinical biomedical research has been transformed by the advent of artificial intelligence, specifically machine learning. Artificial intelligence (AI) can improve risk assessment and diagnosis, as well as boost the precision of clinical outcome prediction and illness classification. Algorithms based on artificial intelligence may be potentially helpful in discovering new needs for myelodysplastic syndrome-affected patients, choosing treatment and assessing minimal residual disease. In this review, we seek to identify the primary mechanisms and uses of artificial intelligence in myelodysplastic syndrome, pointing out its advantages and disadvantages while discussing the possible benefits of using AI pipelines in a therapeutic setting.

Indexed as

artificial intelligenceblood biomarkersdiagnosisflow cytometrymachine learningMDSminimal residual diseasemyelodysplastic syndromesprognostic scoring system

Identifiers

PMID40299419
PMCPMC12024746

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.