ArticleAnnals of nuclear medicine2025
Test for shortening the computation time for imaging of appearance time for cerebral blood using H
Article in Annals of nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveDelayed appearance of blood in the brain may be a pathophysiological indicator of stenosis or occlusion. Image computation for blood appearance generally requires considerable time. Therefore, in this study, we aimed to shorten the computation time using several algorithms and tested their accuracy and precision using examination data and simulations, as well as the computation time.
methodsWe retrospectively analyzed the images of patients with suspected cerebrovascular disorders who underwent PET study with
resultsThe computation time was 28.2 ± 6.2 min, 16.6 ± 3.9 min, and 2.6 ± 1.1 min for modes without fixing, with fixing blood volume, and washout rate, respectively. The mean difference in the appearance time against ROI-based non-linear fitting was less than 1 s with a standard deviation (SD) of approximately 2.5 s for those modes. The images obtained were similar for all three modes. The simulation showed that SD on the estimated appearance times were acceptable, namely < 1.5 s, for these modes.
conclusionThis study suggests the possibility of visualizing appearance time images in the brain with a reasonable computation time of approximately 2.5 min at the minimum and 30 min at the most.
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