Evidence map›Paper›PMID 40299153›Full record

ArticleJournal of computer-aided molecular design2025

Decoding the multifunctional potential of ursolic acid: antioxidant, antiproliferative, molecular dynamics, and biodegradability evaluations of a mangrove-derived terpenoid.

Anaikutti Parthiban, Veeraragavan Sachithanandam, Perumal Lalitha, Priyanka Adhikari, Santhiyagu Prakash, Ramasamy Ramasubburayan, Deepika Dhillon, Jayaraman Muthukumaran, Nambali Valsalan Vinithkumar, Rengurajan Sridhar and 1 more

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In one paragraph

Article in Journal of computer-aided molecular design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anaikutti ParthibanNational Centre for Sustainable Coastal Management, Ministry of Environment, Forest and Climate Change, Anna University Campus, Chennai, Tamil Nadu, 600 025, India.
Veeraragavan SachithanandamNational Centre for Sustainable Coastal Management, Ministry of Environment, Forest and Climate Change, Anna University Campus, Chennai, Tamil Nadu, 600 025, India. pondiunisachin@gmail.com.ORCID 0000-0003-3505-7923
Perumal LalithaNational Centre for Sustainable Coastal Management, Ministry of Environment, Forest and Climate Change, Anna University Campus, Chennai, Tamil Nadu, 600 025, India.
Priyanka AdhikariNational Institute of Pharmaceutical Education and Research, Guwahati, Assam, 781101, India.
Santhiyagu PrakashMarine Biotechnology laboratory, Department of Basic Sciences, Institute of Fisheries Postgraduate Studies, (OMR Campus), Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Vaniyanchavadi, Chennai, Tamil Nadu, 603103, India.
Ramasamy RamasubburayanCentre for Marine and Aquatic Research, Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600 077, India.
Deepika DhillonDepartment of Biotechnology, Sharda School of Bio-Science and Technology, Sharda University, Greater Noida, India.
Jayaraman MuthukumaranDepartment of Biotechnology, Sharda School of Bio-Science and Technology, Sharda University, Greater Noida, India.
Nambali Valsalan VinithkumarMarine Biotechnology Division, Deep Ocean Mission V6 - Advanced Marine Station for Ocean Biology, National Institute of Ocean Technology, Ministry of Earth Sciences, Chennai, Tamil Nadu, 600 100, India.
Rengurajan SridharNational Centre for Sustainable Coastal Management, Ministry of Environment, Forest and Climate Change, Anna University Campus, Chennai, Tamil Nadu, 600 025, India.
Ramachandran PurvajaNational Centre for Sustainable Coastal Management, Ministry of Environment, Forest and Climate Change, Anna University Campus, Chennai, Tamil Nadu, 600 025, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excoecaria agallocha L, a mangrove plant widely used in traditional medication in India, was the focus of this study to evaluate its antioxidant, anticancer, structural, dynamic, and biodegradability properties of its bioactive compound, ursolic acid. This study, a sample (E. agallocha) collected from the tropical Islands ecosystem of South Andaman, India, represents the first report identifying Ursolic acid from the methanolic extract. The structure elucidation of the isolated bioactive compound was characterized using FT-IR,

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsTriterpenesCell Line, TumorCell ProliferationHumansMolecular Docking SimulationMolecular Dynamics SimulationPlant ExtractsUrsolic AcidAntineoplastic Agents, PhytogenicAntioxidantsPlant ExtractsTriterpenesUrsolic AcidAndaman IslandsAnticancerAntioxidantsEnvironmental compatibilityExcoecaria agallochaGC-MSNMRUrsolic acid

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.