ArticleFood and environmental virology2025
Wastewater-Based Epidemiology for Analysis of Human Papillomavirus Infections in a Uruguayan Urban Area.
Article in Food and environmental virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- WEPP: Phylogenetic placement achieves near-haplotype resolution in wastewater-based epidemiology.PLoS computational biology · 2026Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human papillomavirus (HPV) is primarily transmitted through sexual contact and is classified into high- and low-risk genotypes based on their association with cancer development. High-risk (HR) genotypes, such as 16 and 18, among others, have been identified as responsible for the development of cervical cancer while low-risk (LR) genotypes, such as 6 and 11, among others, cause anogenital warts. The aim of this study was to determine the presence of HPV genotypes in wastewater from the wastewater treatment plant of the city of Salto, Uruguay in order to analyze the circulating HPV strains in their population. These samples were subjected to qualitative PCR analysis, and genotypes were identified through sequencing of the DNA products. HPV 6, 16, 31, 66, 81, 84, and 145 were frequently detected in wastewater and HPV 6 and 16 were the prevalent in cytological samples. A great diversity of genotypes was evident in the wastewater of the city. The approach of wastewater-based epidemiology as a representation of the circulating HPV genotypes in the population is adequate and an important tool for molecular epidemiologic studies mainly in developing countries such as Uruguay where information concerning genotypes circulation is scarce.
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