Evidence map›Paper›PMID 40299126›Full record

ArticleBulletin of experimental biology and medicine2025

Aerobic Exercise Affected Lymphocyte Apoptosis by Modulating ROS Release and NLRP3 Inflammasome Activation.

X Lian, Z Guo, J Liu, W Zeng

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

X LianRehabilitation Assessment Department, Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Z GuoRehabilitation Assessment Department, Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
J LiuDepartment of Orthopedics, The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
W ZengFujian Key Laboratory of Rehabilitation Technology, Fuzhou, Fujian, China. zengweiquan@fjtcm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moderate sports training help to enhance spleen-mediated immune function, while prolonged and high-intensity physical exercises could produce an opposite effect. The specific mechanisms underlying the effects of physical load on apoptosis of splenic lymphocytes remain unclear. To address this gap, we developed a model of physical exercises in rats in order to explore the effect of intensity of these exercises on splenic lymphocyte apoptosis and its potential mechanism. We found that high-intensity exercises reduced the CD4

Indexed as

ApoptosisInflammasomesLymphocytesNLR Family, Pyrin Domain-Containing 3 ProteinPhysical Conditioning, AnimalReactive Oxygen SpeciesAnimalsMaleMembrane Potential, MitochondrialOxidative StressRatsRats, Sprague-DawleySpleenInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, ratReactive Oxygen Speciesaerobic exerciseapoptosis of lymphocytesimmune functionNLRP3 inflammasomereactive oxygen species (ROS)

Identifiers

PMID40299126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.