Evidence map›Paper›PMID 40299081›Full record

ReviewJournal of medical systems2025

The Role of Virtual Reality in Personalized Medicine: Advancing Prediction, Prevention, and Participation.

Ilias Miltiadis, Apostolos Skarlis, Pavel Burko

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of medical systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ilias MiltiadisSection of Human Anatomy, Department of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), University of Palermo, Palermo, Italy. ilia.miltykh@you.unipa.it.ORCID http://orcid.org/0000-0002-9130-3255
Apostolos SkarlisSchool of Law, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0009-0001-5272-5834
Pavel BurkoSection of Human Anatomy, Department of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), University of Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0002-1344-9654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of virtual reality (VR) technology into medicine represents a transformative step toward the realization of 4P medicine, characterized by personalization, prediction, prevention, and participation. VR provides an immersive platform for addressing neurological and mental disorders by tailoring virtual environments to individual patient needs, enhancing diagnostic precision, and improving therapeutic outcomes. This paper explores the applications of VR within the framework of 4P medicine, emphasizing its potential in neurorehabilitation, stress reduction, and patient engagement. The personalization aspect of VR enables the design of customized scenarios for therapeutic interventions. Predictive capabilities allow for early detection and mitigation of complications through simulated environments that analyze patient responses. In preventive medicine, VR fosters stress and anxiety reduction, which directly influences patient well-being and quality of life. Participation is enhanced by VR's interactive nature, transforming patients from passive recipients of care to active participants in their treatment journey. Despite its promise, VR faces limitations, including simulator sickness, technical challenges, and accessibility barriers. These factors highlight the need for methodological standardization, improved hardware, and enhanced training for medical professionals. Additionally, a lack of longitudinal studies and safety monitoring systems restricts the widespread clinical adoption of VR. As healthcare systems continue to adapt to technological advancements, VR has the potential to emerge as a pivotal tool in personalized medicine, offering innovative solutions for complex neurological and mental health challenges. By addressing current limitations, VR may redefine patient care and mark a significant milestone in the evolution of evidence-based medical practice.

Indexed as

Patient ParticipationPrecision MedicineVirtual RealityHumansMental DisordersNeurological RehabilitationPreventive MedicineQuality of LifeUser-Computer InterfaceChronic painMindfulnessNeurological rehabilitationPrecision medicinePTSDVirtual reality

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.