Evidence map›Paper›PMID 40299077›Full record

ArticleJournal of materials science. Materials in medicine2025

Dynamic blood compatibility assessment of coronary stents using an innovative pneumatic blood pump to generate physiological flow rates in small sample chambers.

Anne-Sophie Hönicke, Emilia Paz Gross, Simon Beydoun, Felix Pfisterer, Michael Kirschbaum

Abstract read
In one paragraph

Article in Journal of materials science. Materials in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anne-Sophie Hönicke *Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB, Potsdam, Germany.
Emilia Paz Gross *Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB, Potsdam, Germany.
Simon BeydounFraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB, Potsdam, Germany.
Felix PfistererFraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB, Potsdam, Germany.
Michael KirschbaumFraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB, Potsdam, Germany. michael.kirschbaum@izi-bb.fraunhofer.de.ORCID http://orcid.org/0000-0003-3686-8349

Funding

Fraunhofer-Gesellschaft 646016
6 · The paper itself

Abstract

According to ISO 10993-4, shear-dependent processes must be considered in the blood compatibility testing of cardiovascular implants, which demands controlled and physiological flow conditions in the test environment. For very small test objects such as coronary stents with a diameter below 5 mm, this is difficult to achieve, as previous test methods are either unable to represent the required flow velocities in small-lumen sample chambers, or can only do so under high pump shear stress, which in extreme cases can mask the effects of the tiny test objects. In this paper, we present a novel concept for dynamic in vitro models based on pneumatically generated blood flow (AirDrive technology), which can achieve flow rates and velocities up to 450 ml min

Indexed as

Biocompatible MaterialsMaterials TestingStentsBlood Flow VelocityCoronary VesselsHumansStress, MechanicalBiocompatible Materials

Identifiers

PMID40299077
PMCPMC12041065

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.