ArticleInternational urogynecology journal2025
Feasibility of the CT-Image-Guided Colpopexy: A Novel, Needle-Based Sacrospinous Ligament Fixation for Treatment of Vaginal Apical Prolapse.
Article in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Anatomical and Mechanical Safety of the Tissue Anchoring System (TAS®) for Sacrospinous Ligament Fixation.International urogynecology journal · 2026Article
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5 authors.
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Abstract
introduction and hypothesisAlthough several procedures have been developed to increase the precision and reduce the invasiveness of sacrospinous ligament fixation surgery, all surgical approaches require dissection of the vagina to access the paravaginal space and visual or tactile identification of the ligament before deploying a suture or anchor device at the ligament target site. The aim of this study was to develop and demonstrate the feasibility of a minimally invasive, needle-based treatment of vaginal apical prolapse by CT-image-guided anchoring of the vaginal vault to the sacrospinous ligament in cadavers.
methodsA CT-image-guided, needle-based colpopexy procedure was performed on six female cadavers. After the placement of the vaginal probe, each cadaver was CT scanned to identify the target sacrospinous ligament. An anchoring device was inserted through the vaginal probe toward the target ligament. Small anchors, introduced through needle lumens via either transvaginal or transgluteal access, were implanted under the guidance of CT images to anchor the vaginal vault to the sacrospinous ligament. The cadavers were dissected and compared with CT images to evaluate the anatomical locations of the anchors with respect to the anatomical landmarks in the pelvis. Pull-out forces of the implants were also measured.
resultsThirty-two anchors were inserted via transvaginal access, whereas ten anchors were inserted via transgluteal access. CT images revealed that the inserted anchors were implanted in the sacrospinous ligaments (n = 40: 30 transvaginal and 10 transgluteal) or sacrotuberous ligaments (n = 2: transvaginal), as confirmed by dissection of the gluteal region of the cadavers. The mean pullout force was measured as 47.5 N ± 5.0.
conclusionsWe report a feasibility study for the application of novel needle-based colpopexy under CT-image guidance. Further clinical studies are required to implement this method in clinical settings and to demonstrate its safety and effectiveness compared with conventional surgical procedures.
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