Evidence map›Paper›PMID 40298880›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Synchrotron Radiation-Based Tomography of an Entire Mouse Brain with Sub-Micron Voxels: Augmenting Interactive Brain Atlases with Terabyte Data.

Mattia Humbel, Christine Tanner, Marta Girona Alarcón, Georg Schulz, Timm Weitkamp, Mario Scheel, Vartan Kurtcuoglu, Bert Müller, Griffin Rodgers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mattia HumbelBiomaterials Science Center, Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167B/C, Allschwil, 4123, Switzerland.
Christine TannerBiomaterials Science Center, Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167B/C, Allschwil, 4123, Switzerland.ORCID https://orcid.org/0000-0001-6541-2629
Marta Girona AlarcónThe Interface Group, Institute of Physiology, University of Zurich, Winterthurerstrasse 190, Zurich, 8057, Switzerland.
Georg SchulzBiomaterials Science Center, Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167B/C, Allschwil, 4123, Switzerland.
Timm WeitkampSynchrotron SOLEIL, L'Orme des Merisiers, Saint-Aubin, 91190, France.
Mario ScheelSynchrotron SOLEIL, L'Orme des Merisiers, Saint-Aubin, 91190, France.
Vartan KurtcuogluThe Interface Group, Institute of Physiology, University of Zurich, Winterthurerstrasse 190, Zurich, 8057, Switzerland.
Bert MüllerBiomaterials Science Center, Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167B/C, Allschwil, 4123, Switzerland.
Griffin RodgersBiomaterials Science Center, Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167B/C, Allschwil, 4123, Switzerland.

Funding

Agence Nationale de la Recherche ANR-11-EQPX-0031Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 185058Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 213535Swiss National Centre of Competence in Research Kidney Control of Homeostasis 182683
6 · The paper itself

Abstract

Synchrotron radiation-based X-ray microtomography is uniquely suited for post-mortem 3D visualization of organs such as the mouse brain. Tomographic imaging of the entire mouse brain with isotropic cellular resolution requires an extended field-of-view and produces datasets of multiple terabytes in size. These data must be reconstructed, analyzed, and made accessible to domain experts who may have limited image processing knowledge. Extended-field X-ray microtomography is presented with

Indexed as

BrainImaging, Three-DimensionalSynchrotronsX-Ray MicrotomographyAnimalsImage Processing, Computer-AssistedMicebig dataextended field‐of‐viewmulti‐resolution open dataneuroimagingregistrationX‐ray histology

Identifiers

PMID40298880
PMCPMC12302633

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.