Evidence map›Paper›PMID 40298826›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Trace Element Concentrations in Degenerative Lumbar Spine Tissues: Insights into Oxidative Stress.

Mikołaj Dąbrowski, Wojciech Łabędź, Łukasz Kubaszewski, Marta K Walczak, Anetta Zioła-Frankowska, Marcin Frankowski

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mikołaj DąbrowskiAdult Spine Orthopaedics Department, Poznan University of Medical Sciences, 61-545 Poznan, Poland.ORCID 0000-0002-9773-2640
Wojciech ŁabędźAdult Spine Orthopaedics Department, Poznan University of Medical Sciences, 61-545 Poznan, Poland.ORCID 0000-0001-9979-9120
Łukasz KubaszewskiAdult Spine Orthopaedics Department, Poznan University of Medical Sciences, 61-545 Poznan, Poland.
Marta K WalczakDepartment of Internal Medicine and Metabolic Disorders, Poznan University of Medical Sciences, Przybyszewskiego St. 49, 60-355 Poznan, Poland.ORCID 0000-0001-7179-714X
Anetta Zioła-FrankowskaAnalytical Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland.
Marcin FrankowskiDepartment of Analytical and Environmental Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland.ORCID 0000-0001-6315-3758

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degenerative changes are characterized by the formation of vertebral osteophytes, the hypertrophy of facet joints, and narrowing of the intervertebral space. This study aimed to investigate the concentrations of trace elements (Al, As, Se, Zn, Fe, Mo, Cu) in spinal tissues (intervertebral discs, muscle, and bone) of patients with degenerative lumbar spine disease (DLSD) and their potential associations with the disease. The research involved 13 patients undergoing surgery for symptomatic degenerative spine disease. The trace element concentrations were analyzed using chemical and radiographic assessments, with a statistical analysis performed through a Mann-Whitney U-test, Spearman's rank correlation test, principal component analysis (PCA), and canonical discriminant analysis (CDA). The results showed significant variations and correlations among the trace elements across different spinal tissues, suggesting their roles in metabolic and oxidative processes and the pathology of spinal degeneration.

Indexed as

degenerative disc diseasedegenerative spine diseaseICP-OESintervertebral discmicroelementsoxidative elementsspine tissuetrace elements

Identifiers

PMID40298826
PMCPMC12024161

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.