ArticleSao Paulo medical journal = Revista paulista de medicina2025
The burden of healthcare-associated infections in Brazil: multi-hospital point prevalence using a matched case-control study.
Article in Sao Paulo medical journal = Revista paulista de medicina, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Authors and funding
11 authors.
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Abstract
backgroundHealthcare-associated infections (HAIs) have a significant impact on patient care worldwide and have serious implications for the Brazilian healthcare system.
objectivesThis study aimed to describe the trends in HAIs in adult intensive care units (ICUs) using data from a national point-prevalence survey. DESIGN AND
settingA point-prevalence study was conducted in 2019 across adult intensive ICUs in large acute care hospitals in Brazil.
methodsA matched case-control study was performed to assess the risk factors associated with the development of infection.
resultsA total of 386 patients from 15 hospitals were studied, of whom 102 (26.4%; 102/386) were infected, and 76.5% had at least one ICU-acquired infection. In clinical-surgical ICUs (CSU), the prevalence of infections acquired in the unit was 77.9%, whereas in Coronary ICUs (COU), it was 68.7%. There was a predominance of pneumonia (51.0%), mainly caused by Gram-negative non-fermenters, and bloodstream infections (34.4%), predominantly caused by coagulase-negative Staphylococcus (CoNS). In the risk factor analysis, cancer and general antimicrobial use were independently associated.
conclusionThis study found a high burden of HAIs in adult ICUs in Brazil, mainly associated with the high use of antibiotics for infections and a worse prognosis.
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