Evidence map›Paper›PMID 40298598›Full record

ArticleRadiology2025

Order and Timing of Middle Meningeal Artery Embolization as a Perioperative Adjunct to Surgical Evacuation for Chronic Subdural Hematomas: A Multicenter Study.

Georgios S Sioutas, Mohamed M Salem, Okkes Kuybu, Mira Salih, Jane Khalife, Kate Carroll, Edward A Duckworth, Dhrumil Vaishnav, Muhammed Amir Essibayi, Alex Nguyen Hoang and 25 more

Abstract readMulticenter Study
In one paragraph

Article in Radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Preoperative middle meningeal artery embolization is associated with reduced reoperation rates in chronic subdural hematoma.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Feasibility of middle meningeal artery embolization following large craniotomy: A case series.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Georgios S SioutasDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.ORCID 0000-0003-3937-4029
Mohamed M SalemDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.ORCID 0000-0001-7644-2911
Okkes KuybuDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pa.ORCID 0000-0003-0655-5755
Mira SalihDivision of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Teaching Hospital, Boston, Mass.ORCID 0000-0002-8093-6508
Jane KhalifeDepartment of Neurosurgery, Cooper University Health Care, Cooper Medical School of Rowan University, Camden, NJ.
Kate CarrollDepartment of Neurosurgery, University of Washington, Seattle, Wash.
Edward A DuckworthDepartment of Neurosurgery, St Luke's Health System, Boise, Idaho.ORCID 0000-0002-9114-3458
Dhrumil VaishnavDepartment of Neurologic Surgery & Montefiore Einstein Cerebrovascular Research Laboratory, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
Muhammed Amir EssibayiDepartment of Neurologic Surgery & Montefiore Einstein Cerebrovascular Research Laboratory, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0001-8325-2382
Alex Nguyen HoangDepartment of Neurosurgery, Baylor College of Medicine, Houston, Tex.ORCID 0000-0003-1678-3583
Cordell M BakerDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N Medical Dr E, Salt Lake City, UT 84132.ORCID 0000-0003-4843-6906
Aldo A Mendez RuizDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pa.ORCID 0000-0003-0562-2418
Zachary AbecassisDepartment of Neurosurgery, University of Washington, Seattle, Wash.ORCID 0000-0002-2209-8737
Walid K SalahDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N Medical Dr E, Salt Lake City, UT 84132.
Juan F Ruiz RodriguezDepartment of Neurosurgery, University of Washington, Seattle, Wash.ORCID 0009-0000-0587-4231
Iris CharcosDepartment of Neurosurgery, Cooper University Health Care, Cooper Medical School of Rowan University, Camden, NJ.
Gustavo M CortezDepartment of Cerebrovascular and Endovascular Surgery, Baptist Neurologic Institute and Lyerly Neurosurgery, Jacksonville, Fla.ORCID 0000-0003-4227-0378
Sandra NarayananDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pa.ORCID 0000-0002-2915-7963
Oz HaimDepartment of Neurosurgery, Baylor College of Medicine, Houston, Tex.ORCID 0000-0003-0872-6263
Omar TanweerDepartment of Neurosurgery, Baylor College of Medicine, Houston, Tex.ORCID 0000-0002-3219-8109
Ricardo HanelDepartment of Cerebrovascular and Endovascular Surgery, Baptist Neurologic Institute and Lyerly Neurosurgery, Jacksonville, Fla.
Peter KanDepartment of Neurosurgery, Baylor College of Medicine, Houston, Tex.ORCID 0000-0001-6649-4128
Daniel A TonettiDepartment of Neurosurgery, Cooper University Health Care, Cooper Medical School of Rowan University, Camden, NJ.ORCID 0000-0002-9258-1820
Raul G NogueiraDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pa.
Tudor G JovinDepartment of Neurosurgery, Cooper University Health Care, Cooper Medical School of Rowan University, Camden, NJ.
David J AltschulDepartment of Neurologic Surgery & Montefiore Einstein Cerebrovascular Research Laboratory, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0002-5130-1378
Michael J LangDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pa.ORCID 0000-0002-0592-1525
Visish M SrinivasanDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.
Brian T JankowitzDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.ORCID 0000-0001-9306-0763
Ajith J ThomasDepartment of Neurosurgery, Cooper University Health Care, Cooper Medical School of Rowan University, Camden, NJ.
Michael R LevittDepartment of Neurosurgery, University of Washington, Seattle, Wash.ORCID 0000-0003-3612-3347
Christopher S OgilvyDivision of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Teaching Hospital, Boston, Mass.ORCID 0000-0003-4600-8545
Bradley A GrossDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pa.ORCID 0000-0002-6999-7967
Jan-Karl BurkhardtDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.
Ramesh GrandhiDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 N Medical Dr E, Salt Lake City, UT 84132.ORCID 0000-0001-9000-6083

Funding

Chronic Subdural Hematoma Treatment with Embolization vs Surgery or MedicalManagement Study (CHESS)UG3NS128397 · NINDS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CASSARLY, CHRISTY, KAN, PETER TZE MAN · 2023 to 2023
$3.5M
Development of a Wireless Endovascular Nerve Stimulator for Treatment of Refractory Neuropathic PainU18EB029353 · NIBIB · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KAN, PETER TZE MAN, ROBINSON, JACOB T. · 2019 to 2019
$2.3M
NIBIB NIH HHS U18 EB029353NINDS NIH HHS UG3 NS128397
6 · The paper itself

Abstract

Background Chronic subdural hematoma (cSDH) is a common neurosurgical condition, and middle meningeal artery embolization (MMAE) has emerged as a minimally invasive adjunct to surgery, but optimal timing remains unclear. Purpose To investigate radiographic and clinical outcomes of patients with cSDH undergoing MMAE as an adjunct to surgical evacuation, focusing on order and timing of MMAE relative to surgery. Materials and Methods This multicenter, retrospective study included consecutive patients undergoing MMAE adjunct to surgery for cSDH at 10 U.S. centers from September 2018 to September 2023. Clinical and radiographic characteristics and outcomes were examined in MMAE before or after surgery. Primary outcomes included recurrence requiring reoperation and technical success of MMAE. Secondary outcomes included radiographic success, rate of change in hematoma thickness, and functional outcome. Propensity score matching (PSM) balanced baseline characteristics. χ

Indexed as

Embolization, TherapeuticHematoma, Subdural, ChronicMeningeal ArteriesAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesTreatment Outcome

Identifiers

PMID40298598
PMCPMC13150507

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.