Evidence map›Paper›PMID 40298504›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Molecular Characterization of Gram-Negative Bacilli Isolated from a Neonatal Intensive Care Unit and Phenotypic and Molecular Detection of ESBL and Carbapenemase.

Thaís Alves Barbosa, Maria Regina Bentlin, Lígia Maria Suppo de Souza Rugolo, João César Lyra, Adriano Martison Ferreira, Ana Cláudia Moro Lima Dos Santos, Nathalia Bibiana Teixeira, Letícia Calixto Medeiros Romero, Carlos Magno Castelo Branco Fortaleza, Maria de Lourdes Ribeiro de Souza da Cunha

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thaís Alves BarbosaDepartment of Infectious Diseases, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18618-687, Brazil.
Maria Regina BentlinDepartment of Pediatrics, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18618-687, Brazil.
Lígia Maria Suppo de Souza RugoloDepartment of Pediatrics, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18618-687, Brazil.
João César LyraDepartment of Pediatrics, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18618-687, Brazil.
Adriano Martison FerreiraClinical Laboratory-Microbiology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18618-687, Brazil.
Ana Cláudia Moro Lima Dos SantosDepartment of Genetics, Microbiology and Immunology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu 18618-691, Brazil.ORCID 0000-0003-3054-6875
Nathalia Bibiana TeixeiraDepartment of Genetics, Microbiology and Immunology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu 18618-691, Brazil.
Letícia Calixto Medeiros RomeroDepartment of Genetics, Microbiology and Immunology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu 18618-691, Brazil.ORCID 0000-0002-1787-704X
Carlos Magno Castelo Branco FortalezaDepartment of Infectious Diseases, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18618-687, Brazil.
Maria de Lourdes Ribeiro de Souza da CunhaDepartment of Infectious Diseases, Botucatu Medical School, São Paulo State University (UNESP), Botucatu 18618-687, Brazil.ORCID 0000-0001-9079-2723

Funding

National Council for Scientific and Technological Development 303603/2020-8
6 · The paper itself

Abstract

introductionThe increase in the rates of multidrug-resistant bacteria in healthcare environments has been recognized as a global public health problem. In view of the scarcity of data on the neonatal population, this study aimed to provide information on the genotypic and epidemiological characteristics of Gram-negative microorganisms isolated from colonization and infection sites in neonates admitted to a tertiary university center of high complexity.

methodsEnterobacterales and non-fermenting Gram-negative bacilli previously collected in a prospective cohort study were submitted to genotypic identification, detection of extended-spectrum β-lactamases (ESBL), carbapenemases and biofilm production, detection of specific virulence markers in

resultsThe data found here revealed higher rates of infection by

conclusionsEnterobacterales showed average biofilm production, while the majority of non-fermenting Gram-negative bacilli were strong producers. The present data increase our knowledge of the molecular epidemiology of important Enterobacterales species, with emphasis on ESBL-producing

Indexed as

biofilmcolonizationextended-spectrum β-lactamasesinfection

Identifiers

PMID40298504
PMCPMC12024293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.