Evidence map›Paper›PMID 40298466›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Effect of Antimicrobial Compounds on the Survival and Pathogenic Potential of Acid-Adapted

Maria Belén Bainotti, Pilar Colás-Medà, Inmaculada Viñas, Isabel Alegre

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Belén BainottiPostharvest Biology and Technology Unit, Department of Food Technology, Engineering and Science, University of Lleida-AGROTECNIO-CERCA Centre, Av. Rovira Roure 191, 25198 Lleida, Spain.ORCID 0000-0003-4595-6690
Pilar Colás-MedàPostharvest Biology and Technology Unit, Department of Food Technology, Engineering and Science, University of Lleida-AGROTECNIO-CERCA Centre, Av. Rovira Roure 191, 25198 Lleida, Spain.ORCID 0000-0003-3908-7900
Inmaculada ViñasPostharvest Biology and Technology Unit, Department of Food Technology, Engineering and Science, University of Lleida-AGROTECNIO-CERCA Centre, Av. Rovira Roure 191, 25198 Lleida, Spain.ORCID 0000-0001-5182-2520
Isabel AlegrePostharvest Biology and Technology Unit, Department of Food Technology, Engineering and Science, University of Lleida-AGROTECNIO-CERCA Centre, Av. Rovira Roure 191, 25198 Lleida, Spain.ORCID 0000-0002-8153-624X

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) 2022FI_B1 00225Ministerio de Economia y Competitividad PID2019-106645RB-I00
6 · The paper itself

Abstract

backgroundThe consumption of unpasteurized fruit juices poses a food safety risk due to the survival of pathogens such as

methodsThis study evaluated natural antimicrobials (nisin, coumaric acid, citral, sinapic acid, and vanillin) in orange juice as a strategy to ensure the control of these pathogens during the preservation of the non-thermally treated juices.

resultsThe addition of nisin, coumaric, or citral did not alter the juice's physicochemical characteristics, ensuring product quality. Nisin (1-2 mL/L), coumaric acid (0.25-0.5 g/L), and citral (0.25-0.5 mL/L) were the most effective in reducing bacterial populations. The antimicrobial activity of the most effective compounds was then tested against both acid-adapted and non-acid-adapted bacteria in refrigerated juice, applying Weibull and linear decay models to assess bacterial inactivation. Non-acid-adapted

conclusionsThese findings highlight the potential of these antimicrobials for food safety applications, though further studies should explore their mechanisms and combinations for enhanced efficacy.

Indexed as

acid adaptationcoumaric acidfoodborne pathogensgastrointestinal simulationnisinorange juice

Identifiers

PMID40298466
PMCPMC12024196

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.