Evidence map›Paper›PMID 40298396›Full record

ArticleJournal of bacteriology2025

Genome-wide characterization of hypothiocyanite stress response in

Julia D Meredith, Michael J Gray

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julia D MeredithDepartment of Microbiology, School of Medicine,The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Michael J GrayDepartment of Microbiology, School of Medicine,The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-7112-4188

Funding

Molecular Mechanisms of Bacterial Stress Response Relevant to Host-Microbe InteractionsR35GM124590 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael Jeffrey Gray · 2017 to 2026
$3.5M
NIGMS NIH HHS R35 GM124590NIGMS NIH HHS R35GM124590
6 · The paper itself

Abstract

Oxidative stress is one of the major methods of microbial population control and pathogen clearing by the mammalian immune system. The methods by which bacteria are able to escape damage by host-derived oxidants such as hydrogen peroxide (H IMPORTANCE: Understanding how bacteria sense and respond to oxidative stress provides insights into how our bodies interact with the microbial population within us. In this study, we have characterized the genetic response of

Indexed as

Escherichia coliGenome, BacterialOxidative StressThiocyanatesEscherichia coli ProteinsGene Expression Regulation, BacterialHydrogen PeroxideHypochlorous AcidOxidantsEscherichia coli ProteinsHydrogen PeroxideHypochlorous Acidhypothiocyanite ionhypothiocyanous acidOxidantsThiocyanatesoxidative stress

Identifiers

PMID40298396
PMCPMC12096828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.