Evidence map›Paper›PMID 40298296›Full record

Trial reportThe Journal of asthma : official journal of the Association for the Care of Asthma2025

Video directly observed therapy to improve inhaler technique among pediatric patients with persistent asthma.

Lina Mahmood, Kasturi R Sarkar, Kaymon Neal, Rita C Brown, Andrew W Brown, Scott Stewart, Robert D Pesek, Akilah A Jefferson, Tamara T Perry

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of asthma : official journal of the Association for the Care of Asthma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lina MahmoodDepartment of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.
Kasturi R SarkarDepartment of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.
Kaymon NealDepartment of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.
Rita C BrownDepartment of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.
Andrew W BrownDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Scott StewartDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Robert D PesekDepartment of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.
Akilah A JeffersonDepartment of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.
Tamara T PerryDepartment of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.

Funding

Multifactorial Asthma Determinants in Underresourced Pediatric PopulationsK23HL174407 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI Akilah Andrea Jefferson · 2024 to 2026
$494k
NHLBI NIH HHS K23 HL174407NHLBI NIH HHS L60 HL159842
6 · The paper itself

Abstract

objectiveTo assess the feasibility of at-home video directly observed therapy (vDOT) among pediatric patients with asthma to learn and retain proper inhaler technique.

methodsWe conducted a randomized pilot study with 22 children with persistent asthma aged 6-11 years who were newly prescribed an asthma controller inhaler. Patients underwent 1:1 randomization into one group receiving standard inhaler education during clinic and another receiving standard education plus vDOT for 30 days. vDOT is a method by which trained professionals observe patients self-administering medications through a virtual platform to monitor adherence and proper medication use. We measured inhaler technique, age-appropriate Asthma Control Test (ACT) score, symptom-free days, and healthcare utilization in both groups at 3 months.

resultsMedian inhaler technique accuracy percentage score was 88% (IQR 66, 100) for vDOT participants compared to 75% (IQR 38, 88) for controls (

conclusionvDOT is a viable technique to provide initial and continual education and real-time feedback on inhaler technique after the initial education provided in clinic.

Indexed as

Anti-Asthmatic AgentsAsthmaNebulizers and VaporizersPatient Education as TopicAdministration, InhalationChildFeasibility StudiesFemaleHumansMalePilot ProjectsSelf AdministrationVideo RecordingAnti-Asthmatic Agentsasthma symptom controlinhaler technique retentionmedication adherencemedication deliverypatient educationpediatric asthmaVideo directly observed therapy

Identifiers

PMID40298296
PMCPMC12353540

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.