Evidence map›Paper›PMID 40298267›Full record

ArticleJournal of water and health2025

Characterization of enteric pathogens in Harare, Zimbabwe using environmental surveillance and metagenomics.

Samantha Cheung, Nicolette A Zhou, Vurayai Ruhanya, Kelsey J Jesser, Ignitious Nezomba, John Musvibe, Brendon Manyisa, George Nyandoro, Paradzai Chibukira, Arnold Mukaratirwa and 4 more

Abstract read
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In one paragraph

Article in Journal of water and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Samantha CheungUniversity of Washington, Seattle, WA, USA.
Nicolette A ZhouUniversity of Washington, Seattle, WA, USA.
Vurayai RuhanyaUniversity of Zimbabwe, Harare, Zimbabwe.
Kelsey J JesserUniversity of Washington, Seattle, WA, USA.
Ignitious NezombaUniversity of Zimbabwe, Harare, Zimbabwe.
John MusvibeUniversity of Zimbabwe, Harare, Zimbabwe.
Brendon ManyisaUniversity of Zimbabwe, Harare, Zimbabwe.
George NyandoroUniversity of Zimbabwe, Harare, Zimbabwe.
Paradzai ChibukiraUniversity of Zimbabwe, Harare, Zimbabwe.
Arnold MukaratirwaUniversity of Zimbabwe, Harare, Zimbabwe.
Simon Takawira MuserereCity of Harare, Harare, Zimbabwe.
Kudzai MasundaCity of Harare, Harare, Zimbabwe.
Angelo OngUniversity of Washington, Seattle, WA, USA.
John Scott MeschkeCity of Harare, Harare, Zimbabwe E-mail: jmeschke@uw.edu.ORCID https://orcid.org/0000-0002-8983-9042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High diarrheal disease burden remains an urgent concern in low- and middle-income countries, greatly affecting children under the age of 5 years and those living with HIV and AIDS. Treatment of infectious diseases has also become increasingly difficult with the rapid rise of antimicrobial resistance (AMR). Environmental surveillance of wastewater can supplement gaps in clinical surveillance as residents on a sewage system contribute to the wastewater, providing simple, composite samples that can improve understanding about both pathogens and AMR in the community. This study evaluated the effectiveness of environmental surveillance with shotgun metagenomics as a tool to characterize a broad range of enteric pathogens, antibiotic resistance genes, and virulence factor genes (VFGs) in wastewater from six neighborhoods in Harare, Zimbabwe. Alpha and beta diversity of the microbial community were similar between high-income and low-income suburbs. Enteric pathogens of high AMR and clinical concern, including

Indexed as

BacteriaEnvironmental MonitoringMetagenomicsWastewaterDrug Resistance, BacterialHumansSewageZimbabweSewageWastewaterantimicrobial resistanceenteric pathogensenvironmental surveillanceshotgun metagenomicswastewaterZimbabwe

Identifiers

PMID40298267

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.