ArticleBiomacromolecules2025
Antibacterial and Cell-Adhesive Poly(2-ethyl-2-oxazoline) Hydrogels Developed for Wound Treatment:
Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Recent advances in lipid nanoparticles for cancer vaccine delivery: Challenges and future perspectives.International journal of pharmaceutics: X · 2026Review
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4 authors.
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Abstract
Poly(2-alkyl-2-oxazoline) (PAOx) polymers are promising materials due to their tunable properties. In this study, poly(2-ethyl-2-oxazoline) (PEtOx) was methacrylated after partial hydrolysis to produce methacrylated poly(2-ethyl-2-oxazoline) (POx-MA), which was subsequently used to synthesize novel hydrogels. Interpenetrating polymer networks (IPN) were developed by combining POx-MA with methacrylated gelatin (GelMA). Compression tests revealed that GelMA exhibited the highest mechanical strength (199 ± 21 kPa), followed by the IPN POx-MA:GelMA (112 ± 27 kPa) and POx-MA (15 ± 5 kPa). However, in scratch wound healing tests, this order was reversed, with POx-MA exhibiting the highest closure (67 ± 8%), followed by the IPN (51 ± 2%) and GelMA (42 ± 1%) in 48 h. Cell viability exceeded 90% with all of the hydrogels. The study showed that partial hydrolysis and the resultant free amine groups in POx-MA enhanced cell adhesion. Moreover, POx-MA containing hydrogels demonstrated high antibacterial activity against
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