Evidence map›Paper›PMID 40298148›Full record

ArticleJournal of oral rehabilitation2025

Supragingival Microbiota Alterations in Individuals With Sleep Bruxism: A Pilot Study.

Athénaïs Collard, Alban Mathieu, Paolo Landa, Annik Pelletier, Gilles J Lavigne, Arnaud Droit, Nelly Huynh, Vanessa P Houde

Abstract read
In one paragraph

Article in Journal of oral rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Athénaïs CollardFaculté de Médecine Dentaire, Groupe de Recherche en Ecologie Buccale (GREB), Université Laval, Quebec City, Canada.
Alban MathieuCentre de Recherche du CHU de Québec-Université Laval Site CHUL, Quebec City, Canada.
Paolo LandaDépartement d'Opérations et Systèmes de Décision, Université Laval, Quebec City, Canada.
Annik PelletierFaculté de Médecine Dentaire, Université Laval, Quebec City, Canada.
Gilles J LavigneFaculté de Médecine Dentaire, Université de Montréal, Montreal, Canada.
Arnaud DroitCentre de Recherche du CHU de Québec-Université Laval Site CHUL, Quebec City, Canada.
Nelly HuynhFaculté de Médecine Dentaire, Université de Montréal, Montreal, Canada.ORCID https://orcid.org/0000-0003-4836-2476
Vanessa P HoudeFaculté de Médecine Dentaire, Groupe de Recherche en Ecologie Buccale (GREB), Université Laval, Quebec City, Canada.ORCID https://orcid.org/0000-0003-1932-805X

Funding

Fondation de l'Université Laval
6 · The paper itself

Abstract

backgroundSleep bruxism (SB) is an oral behaviour associated to jaw clenching or grinding of the teeth. Its aetiology is most likely multifactorial; however, recent studies suggested that SB is associated with activation of the sympathetic nervous system. Dysbiosis of the oral microbiota is linked to oral and systemic diseases. The relationship between supragingival microbiota and SB remains unexplored.

objectiveThis study aimed to investigate the association between SB and the composition of the supragingival microbiota.

methodsNineteen metabolically and orally healthy subjects were recruited. After SB diagnosis, supragingival microbiota samples were collected. Microbial DNA was extracted and subjected to 16S rRNA gene sequencing. Amplicon sequence variant (ASV) analysis method was used to correlate the composition of supragingival microbiota with SB.

resultsBacterial diversity decreased in the SB group. ASV_200 (Actinomyces) and ASV_94 (Morococcus) were enriched in the SB individuals, whereas ASV_405 (Morococcus) was enriched in the controls. The role of the decreased bacterial diversity as well as the enrichment of specific ASV in the mechanism explaining the genesis of SB remain to be determined.

conclusionThe differences in the composition of the supragingival microbiota may lead to the assessment of important questions in the fields of oral microbiota composition and sleep medicine.

Indexed as

DysbiosisGingivaMicrobiotaSleep BruxismAdultFemaleHumansMaleMiddle AgedPilot ProjectsRNA, Ribosomal, 16SRNA, Ribosomal, 16S16S rRNA gene sequencingcomputational biologysleep bruxismsupragingival microbiota

Identifiers

PMID40298148
PMCPMC12408962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.