ArticleJournal of applied physiology (Bethesda, Md. : 1985)2025
Greater negative affective responsivity to daily stressors is positively related to urinary norepinephrine excretion in middle-aged adults.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Affective Responsivity and Cardiovascular Stress Reactivity in Depression.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Lean Mice Exposed to Early Life Stress Exhibit Increased Basal Sympathetic Tone and Blunted Parasympathetic Activation in Response to High Salt Diet.Comprehensive physiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Despite mounting evidence that greater affective responsivity to naturally occurring daily stressors is associated with increased risk of cardiovascular diseases (CVDs), few studies have examined dysregulation of the sympathetic nervous system as a potential mechanism. We hypothesized that greater affective responsivity to daily stressful events would be related to increased urinary catecholamine excretion. Daily stress processes (8-day daily diary) were assessed in 715 middle-aged adults (56 ± 11 yr; 57% female) from the Midlife in the United States Study. Urinary norepinephrine and epinephrine concentrations were also measured (24 h; normalized to creatinine). Multilevel modeling was used to calculate negative and positive affective responsivity (i.e., the slope of the within-person differences in negative and positive affect on stressor days compared with stressor-free days). Analyses controlled for relevant covariates (e.g., sex, age, affect on stressor-free days, etc.). On stressor days, negative affect increased (0.1 ± 0.2 stressor-free days vs. 0.3 ± 0.4 au stressor days;
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Registered trials
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