ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025
Tracheostomy Tube Change Versus PEEP Titration on Tracheostomy-Dependent Infants With Airway Malacia and Ventilator Instability.
Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate the impact of positive end-expiratory pressure (PEEP) titrations or tracheostomy size change (trach change) on ventilation stability in infants with tracheobronchomalacia. STUDY
designA retrospective chart review.
settingTertiary care children's hospital from 2015 to 2023.
methodsA retrospective chart review on ventilator and tracheostomy-dependent patients <1 year of age. Demographics, bronchoscopic findings, and ventilator outcomes within 14 days were recorded. Analysis was performed with chi-square, Fisher's exact, binomial regression analysis, and two-tailed t tests.
resultsOf 71 patients (66% male, median 6.1 months old [interquartile range, IQR, 4.6-7.3]) who underwent 74 initial bronchoscopies, the PEEP titration cohort (n = 37) experienced an improvement (narrower) in 24-hour mean ventilatory ranges (peak inspiratory pressure [PIP] 5.6 pre vs 2.9 post, P = .01; fraction of inspired oxygen [FiO
conclusionPEEP titration was associated with improved PIP and FiO
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