SynthesisJournal of clinical ultrasound : JCU2025
Comparison of the Diagnostic Performance of Ovarian Adnexal Reporting Data System (O-RADS) With IOTA Simple Rules and ADNEX Model for Classifying Adnexal Masses: A Head-To-Head Meta-Analysis.
Synthesis in Journal of clinical ultrasound : JCU, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of the Diagnostic Performance of Ovarian Adnexal Reporting Data System (O-RADS) With IOTA Simple Rules and ADNEX Model for Classifying Adnexal Masses: A Head-To-Head Meta-Analysis.Journal of clinical ultrasound : JCU · 2025Pooled it
- Comparative Diagnostic Performance of IOTA Simple Rules, the ADNEX Model, and ACR O-RADS in a Selected Surgical Cohort of Adnexal Masses: A Retrospective Study.Journal of clinical medicine · 2026Article
- Comparative Diagnostic Performance of IOTA Simple Rules, O-RADS US, and Subjective Assessment in Differentiating Benign from Malignant Adnexal Masses.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Article
- Review
- Early-fusion hybrid CNN-transformer models for multiclass ovarian tumor ultrasound classification.Frontiers in artificial intelligence · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the diagnostic accuracy of O-RADS (Ovarian Reporting and Data System) and IOTA (international Ovarian Tumor Analysis group) simple rules (SR) and ADNEX (Assessment of Different NEoplasias in the adnexa) model for discriminating benign from malignant adnexal masses using meta-analysis.
methodsA systematic search of studies comparing O-RADS with SR and/or ADNEX in the same set of patients with an adnexal mass was performed in Medline, Web of Science, and Scopus databases from January 2020 to September 2023. Quality was assessed using the QUADAS-2 tool. Quantitative meta-analysis was performed.
resultsNine articles comprising 3924 women (3979 adnexal masses) were ultimately included after exclusions. Three studies compared O-RADS versus SR, three studies compared O-RADS versus ADNEX, and three studies compared all three methods. The risk of bias was high for patient selection in QUADAS-2 in all studies. Six studies compared O-RADS versus SR; no significant differences were found (pooled sensitivity and specificity of O-RADS and IOTA SR were 94.0% and 77.0%, and 91.0% and 87.0%, respectively. p = 0.2204). Six studies compared O-RADS versus ADNEX; no significant differences were found (pooled sensitivity and specificity of O-RADS classification system and ADNEX were 95.0% and 79.0%, and 91.0% and 88.0%, respectively. p = 0.2307).
conclusionO-RADS classification has a similar diagnostic performance to IOTA SR and ADNEX for discriminating benign and malignant adnexal masses.
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