ArticleNucleic acids research2025
OriV-Finder: a comprehensive web server for bacterial plasmid replication origin analysis.
Article in Nucleic acids research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Genetic Elements Associated with the Acquired Resistome of the Gut Microbiota in a Broiler Rooster Flock in Hungary.Animals : an open access journal from MDPI · 2026Article
- Complete genome sequences ofMicrobiology resource announcements · 2026Article
- Computational prediction of replication origins: a comparative review of methods, benchmarks, and trends from heuristics to deep learning.Briefings in bioinformatics · 2026Review
- Origin of replication discovery for environmentally isolatediScience · 2026Article
- Extensive mobilome dynamics in a widespread endosymbiont: long read metagenomics reveal dimeric plasmids and highly fragmented prophages in Wolbachia from Culex pipiens.Research square · 2026Article
- Complete genome sequence ofMicrobiology resource announcements · 2026Article
- PlasAnn: a curated plasmid-specific database and annotation pipeline for standardized gene and function analysis.Nucleic acids research · 2026Article
- Megaplasmids associate withbioRxiv : the preprint server for biology · 2025Article
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Authors and funding
2 authors.
Funding
Abstract
To rapidly identify and systematically analyse the vegetative replication origins (oriVs) of bacterial plasmids, we present OriV-Finder, a comprehensive web server for bacterial plasmid replication origin analysis. To fulfil this purpose, we collected 470 replication initiation proteins (RIPs) reported in the literature, identified 35 conserved domains associated with RIPs, and summarized conserved features of oriVs for various replication initiation mechanisms. Therefore, OriV-Finder could accurately identify the homologous genes of RIPs and then assess the likelihood of each intergenic sequence as a potential oriV based on the information of RIPs and conserved features. Consequently, the potential oriVs could be designated using a priority-based scoring system. As a user-friendly web server, OriV-Finder integrates visualization modules of oriVs, RIPs, and genomes, which facilitates the analysis and validation of oriVs. OriV-Finder is freely available to all users without any login requirement at https://tubic.org/OriV-Finder/.
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