Evidence map›Paper›PMID 40297919›Full record

Trial reportClinical oral implants research2025

A Randomised Controlled Trial Evaluating 3-Year Survival Rates and Technical Complications of Screw-Retained Hybrid Abutment Crowns on Two-Piece Zirconia and Titanium Implants.

Guido Sterzenbach, Kristin Richter, Klara Alpen, Hediyeh Khoshreza, Florian Beuer, Theodor Thiele

Abstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in Clinical oral implants research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guido SterzenbachDepartment of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.ORCID 0000-0003-0510-1911
Kristin RichterMVZ Zahnmedizin Pankow, Dentalzentrum Pankow, Berlin, Germany.
Klara AlpenMVZ Zahnmedizin Pankow, Dentalzentrum Pankow, Berlin, Germany.
Hediyeh KhoshrezaMVZ Zahnmedizin Pankow, Dentalzentrum Pankow, Berlin, Germany.
Florian BeuerDepartment of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.ORCID 0000-0003-0246-790X
Theodor ThieleMVZ Zahnmedizin Pankow, Dentalzentrum Pankow, Berlin, Germany.

Funding

Oral Reconstruction Foundation
6 · The paper itself

Abstract

objectivesThis study compares the cumulative survival and technical complications of screw-retained implant-supported lithium disilicate crowns (SICs) on polyether ketone ketone (PEKK) base abutments and zirconia implants with those of titanium base abutments and titanium implants. MATERIALS AND

methodsSixty participants were randomly and evenly assigned to receive zirconia or titanium implants. Survival and technical complications were assessed at 6 weeks after crown placement (baseline) up to 36 months. The cumulative survival of the SICs was analysed as a non-inferiority design, assuming that the difference between the titanium group and the zirconia group is not more than 10%. Technical complications were assessed based on modified USPHS criteria and Pink Aesthetic Score (PES).

resultsIn the zirconia group, three early implant failures occurred; all of them were successfully revised. After baseline, three implants in the zirconia group were lost due to insufficient osseointegration, and therefore the SICs have to be categorised as failures even though none of the SICs failed. The non-inferiority of the zirconia group could not be confirmed, as the cumulative survival was 10.7% lower compared to the titanium group (100%). The technical complication rate was low, with no statistically significant difference between the groups. The PESs improved significantly compared to baseline, with no significant difference between the groups at 12 months.

conclusionHybrid abutment SICs with PEKK base abutments on two-piece zirconia implants could be an alternative to hybrid abutments SICs with titanium base on titanium implants. However, the lower osseointegration rate of the zirconia implants has to be considered.

trial registrationThis study was registered in the German Clinical Trial Register (Deutsches Register Klinischer Studien) (number: DRKS00014866).

Indexed as

CrownsDental AbutmentsDental Implant-Abutment DesignDental ImplantsDental Prosthesis, Implant-SupportedDental Restoration FailureTitaniumZirconiumAdultDental PorcelainDental Prosthesis DesignFemaleHumansMaleMiddle AgedDental ImplantsDental Porcelainlithia disilicateTitaniumZirconiumzirconium oxideceramic implantshybrid abutment crownrandomised controlled trialscrew‐retainedtitaniumtwo‐piece implantszirconia

Identifiers

PMID40297919
PMCPMC12319353

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.