ArticleBiomedical reports2025
Brain magnetic resonance imaging findings in hyperammonemic hepatic encephalopathy: A case series and literature review.
Article in Biomedical reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Hyperammonemic encephalopathy is a life-threatening condition that can lead to coma and death due to brain edema and intracranial hypertension. The current study presents the clinical and magnetic resonance imaging (MRI) findings of 5 cases of acute hyperammonemic hepatic encephalopathy. MRI images of all 5 patients showed diffuse cortical swelling affecting the frontal, temporal, and parietal lobes, as well as the insular cortex and cingulate gyri. However, the underlying white matter, peri-rolandic area, and posterior occipital lobe remained unaffected. These specific brain MRI features are more commonly observed in cases with 165 µmol/l or higher ammonia levels, suggesting a potential correlation. Further studies are needed to confirm this association.
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