ArticlePlastic and reconstructive surgery. Global open2025
Hyaluronic Acid Filler Usage and Technique for the Facial Upper Third: A Comprehensive Review.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Chronic Maxillary Sinusitis Due to Material Compatible with Hyaluronic Filler-A Case Report.Clinics and practice · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Facial aging entails complex alterations across various tissues, prompting individuals to seek aesthetic interventions. The anatomical complexities of the facial upper third and its proximity to vital vascular structures provide inherent risks. We aim to identify and elucidate the safety considerations and avenues for improvement regarding established injection sites and techniques for hyaluronic acid fillers in this area, encompassing the forehead and temporal region. Methods: We conducted a comprehensive literature search across PubMed, Embase, LILACS, and OpenGrey. Eligible studies were analyzed for injection sites, techniques, safety considerations, and anatomical landmarks. Qualitative synthesis and critical appraisal were used to identify trends, variations, and areas of consensus or controversy. Additionally, medical illustrations were created to deliver a practical overview. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist and the Joanna Briggs Institute's scoping review recommendations. Results: We included 7 studies in the review. Common injection sites included frontal and temporal regions, with variations in techniques noted across studies. Trends in filler placement and techniques were observed alongside several areas of controversy requiring further investigation. Conclusions: We underscore the absence of a standardized approach to hyaluronic acid filler injection sites and techniques for the facial upper third. Integrating anatomical knowledge with empirical evidence will be paramount in developing standardized techniques that prioritize patient safety and enhance treatment efficacy.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.