ArticleInfection and drug resistance2025
Impact of Multimodal Fast-Track Protocols on Recovery in End-Stage Hepatic Alveolar Echinococcosis Patients Undergoing ex vivo Liver Resection and Autotransplantation: a Preliminary Study.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: While ex vivo liver resection combined with autotransplantation has been reported from various perspectives, the use of fast-track protocols for this procedure in treating end-stage hepatic alveolar echinococcosis has not been documented. Methods: We retrospectively analyzed the outcomes of 21 patients with end-stage hepatic alveolar echinococcosis who underwent ex vivo liver resection and autotransplantation, followed by a fast-track recovery protocol at our institution between 2014 and 2017. Results: All patients successfully underwent liver autotransplantation with no intraoperative mortality. Postoperative hospital stays ranged from 4 to 51 days, with an average of 23.5 days. Hospital costs averaged $3 million (range $1.94-4.07 million). Twelve patients experienced postoperative complications, with four classified as Clavien-Dindo grade III or higher. Two patients died due to intra-abdominal bleeding and acute cerebral hemorrhage, respectively. Nineteen patients were followed for a median of 16.2 months (range 3-38 months), with no recurrence of hepatic alveolar echinococcosis. Conclusion: Fast-track protocols are safe and effective in the context of ex vivo liver resection and autotransplantation.
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