SynthesisFrontiers in aging neuroscience2025
Meta-analysis of the effects of multi-component exercise on cognitive function in older adults with cognitive impairment.
Synthesis in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effects of different types of physical exercise interventions on aggressive behavior among children and adolescents: a network meta-analysis.Frontiers in psychology · 2026Pooled it
- Multicomponent exercise interventions for cognitive function in patients with mild cognitive impairment: a summary of best evidence.Frontiers in rehabilitation sciences · 2025Pooled it
- The efficacy versus evidence quality of multicomponent exercise for cognitive health in older adults: an umbrella review.Frontiers in aging neuroscience · 2025Pooled it
- Effects of Combined Physical and Cognitive Stimulation on Go/No-Go Performance in Older Women: A Pilot and Feasibility Study.Journal of Intelligence · 2026Article
- Nonlinear Gait Variability and the Role of Cognitive-Physical Exercise in Mitigating Mobility Decline in Institutionalized Older Adults with Cognitive Impairment.Journal of functional morphology and kinesiology · 2026Article
- Myokine Cathepsin B as a Key Muscle-Brain Axis Regulator Mediates Treadmill-Running-Induced Hippocampal Neurogenesis and Cognitive Improvement in Mice.Research (Washington, D.C.) · 2026Article
- Four-Limb Coordinated Training and Neuroplasticity in Older Adults with Cognitive Frailty: Mechanisms and Clinical Evidence.Clinical interventions in aging · 2026Review
- Move to Remember: The Role of Physical Activity and Exercise in Preserving and Enhancing Cognitive Function in Aging-A Narrative Review.Geriatrics (Basel, Switzerland) · 2025Review
- Brief mind-body exercise in high-latitude aging: reduced sedentarism and domain-specific cognitive/social benefits.Frontiers in public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise has been widely recognized as an effective regimen in mitigating cognitive decline. However, the effect of multi-component exercise (i.e., combination of two or more types of exercise) on cognitive function and its subdomains in older adults remains unclear. This meta-analysis aimed to explore the effects of multi-component exercise on cognitive functions in elderly individuals with cognitive impairment and identify optimal prevention and treatment strategies. A systematic search was conducted on PubMed, EBSCOhost, Web of Science, and Embase to identify relevant randomized controlled trials assessing the effect of multi-component exercise on cognitive function in the elderly. Thirteen studies with 1,776 participants were included in the analysis using Revman 5.4 software. The results showed that multi-component exercise had a significant effect on mitigating cognitive function decline in the elderly, with a pooled effect size of SMD = 0.31 (95% CI: 0.08, 0.55;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.