ArticleJournal of pain research2025
"Zhibian (BL54) to Shuidao (ST28)" Acupuncture Manipulation Combined with Analgesics in Postoperative Pain Management for Patients with Mixed Hemorrhoids: A Randomized Controlled Trial Protocol.
Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Effects of Preemptive Analgesia Using Wrist-Ankle Acupuncture on Postoperative Pain and Urinary Retention After Haemorrhoidectomy: A Randomised, Three-Arm, Clinical Trial.Journal of pain research · 2026Trial
- Effect of transcutaneous electrical acupoint stimulation at Zusanli (ST36) on postoperative pain following mixed hemorrhoidectomy: a retrospective study.American journal of translational research · 2026Article
- Bridging Traditions: Integrating TCM Into ERAS for Enhanced Gastrointestinal Recovery -A Scoping Review.Drug design, development and therapy · 2026Article
- Wrist-Ankle Acupuncture Relieves Postoperative Pain After Milligan-Morgan Hemorrhoidectomy for Mixed Hemorrhoids: A Randomized Controlled Clinical Trial.Journal of pain research · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Mixed hemorrhoids patients often face severe postoperative pain, typically treated with Non-steroidal anti-inflammatory drugs (NSAIDs) or opioids, which may lead to gastrointestinal and Central Nervous System (CNS) side effects. The "Zhibian (BL54) to Shuidao (ST28)" manipulation acupuncture combined with analgesics shows promise as a safe and effective alternative. Thorough randomized controlled trials (RCTs) are crucial for determining the effectiveness and safety when used in conjunction with pain relievers. Patients and Methods: This double-blind randomized controlled trial aims to assess the effectiveness and safety of the acupuncture method connecting the "Zhibian (BL54)" and "Shuidao (ST28)" points combined with analgesics in alleviating pain following surgery for mixed hemorrhoids. A total of 104 patients who meet diagnostic criteria and undergo Milligan-Morgan open hemorrhoidectomy (MMH) will be randomized into control (n = 52) or acupuncture (n = 52) groups. The control group will receive diclofenac sodium, while the acupuncture group will additionally undergo the "Zhibian (BL54) to Shuidao (ST28)" manipulation acupuncture. The intervention will span a duration of five days, with data collection occurring both prior to and following the intervention. Primary outcomes include Visual analogue scale (VAS) scores for pain, with secondary outcomes assessing analgesic efficiency, increased pain medication use, and pain interference in daily activities. Statistical analysis will be conducted utilizing SPSS software, version 26.0. Discussion: This forward-looking, randomized study aims to assess the effectiveness of combining acupuncture with medication in alleviating postoperative pain for individuals suffering from mixed hemorrhoids, wih the goal of establishing a safe and potent therapeutic strategy and broadening the clinical applications of this intervention. Conclusion: This randomized study evaluates the effectiveness of combining acupuncture with medication to relieve postoperative pain in patients with mixed hemorrhoids, aiming to establish a safe and effective treatment strategy and expand its clinical use.
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