Evidence map›Paper›PMID 40297449›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Ocular Manifestations in a Cohort of Patients with Mpox in the Democratic Republic of the Congo 2007 - 2011.

Placide Mbala-Kingebeni, Nam V Nguyen, Jean-Claude Mwanza, Jessica Carag, Susanne Linderman, Tolulope Fashina, Eddy Kinganda, Tony Wawina-Bokalanga, Amuri Aziza, Jean-Claude Makangara-Cigolo and 16 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors.

Placide Mbala-KingebeniInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Nam V NguyenStanley M. Truhlsen Eye Institute, Department of Ophthalmology, University of Nebraska Medical Center, Omaha, Nebraska, United States.
Jean-Claude MwanzaDepartment of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina, United States.
Jessica CaragEmory University School of Medicine, Atlanta, Georgia, United States.
Susanne LindermanEmory University School of Medicine, Atlanta, Georgia, United States.
Tolulope FashinaStanley M. Truhlsen Eye Institute, Department of Ophthalmology, University of Nebraska Medical Center, Omaha, Nebraska, United States.
Eddy KingandaInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Tony Wawina-BokalangaInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Amuri AzizaInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Jean-Claude Makangara-CigoloInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Emmanuel Hasivirwe VakaniakiInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.ORCID 0009-0006-0795-7157
Yvon AntaInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Jepsy YangoInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Olivier TshianiInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
Jason KindrachukDepartment of Medical Microbiology & Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.ORCID 0000-0002-3305-7084
Laurens LiesenborghsDepartment of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0001-5616-8548
Martine PeetersTransVIHMI, Université de Montpellier, INSERM, IRD, Montpellier, France.
Eric DelaporteTransVIHMI, Université de Montpellier, INSERM, IRD, Montpellier, France.
Anne W RimoinDepartment of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California-Los Angeles, California, United States.
John W HugginsDivision of Medicine, US Army Medical Institute of Infectious Diseases, Fort Detrick, Maryland, United States.
Therese Riu-RoviraHôpital Général de Référence de Kole, Kole-sur-Lukenie, Democratic Republic of the Congo.
Steve M AhukaInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
James W MartinRegional Health Command-Atlantic, Ft Belvoir, Virginia, United States.
Ian CrozierClinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
Steven YehStanley M. Truhlsen Eye Institute, Department of Ophthalmology, University of Nebraska Medical Center, Omaha, Nebraska, United States.
Jean-Jacques MuyembeInstitut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.

Funding

Pathogenesis of Uveitis in Ebola Virus Disease SurvivorsR01EY029594 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI YEH, STEVEN · 2019 to 2023
$2.9M
NEI NIH HHS R01 EY029594
6 · The paper itself

Abstract

This report describes the ocular manifestations in a cohort of patients with Clade I mpox evaluated in the Democratic Republic of the Congo (DRC) from 2007 to 2011, as well as the clinical course of a pediatric patient with mpox associated with ocular disease. Among 216 patients, ocular manifestations were observed in 8.3% of the patients, including conjunctivitis, eyelid lesions, eyelid swelling, eye pain, orbital swelling, keratitis, and corneal staphyloma. These findings highlight the broad spectrum of ocular manifestations with potential sight-threatening consequences in patients with mpox.

Indexed as

Clade I monkeypox virusconjunctivitiscorneal staphylomaDemocratic Republic of the Congoeyelid edemakeratitisMpoxocular manifestations

Identifiers

PMID40297449
PMCPMC12036391

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.