Evidence map›Paper›PMID 40297427›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Re-emergence of Yellow Fever Virus in Brazil: Evidence from Forest and peri-urban Settings.

Valnete das Graças Dantas Andrade, Talita Émile Ribeiro Adelino, Vagner Fonseca, Keldenn Melo Farias Moreno, Luiz Marcelo Ribeiro Tomé, Luiz Augusto Pereira, Debora Glenda Lima de La-Roque, Ana Maria Bispo de Filippis, Daniel Garkauskas Ramos, Dario Brock Ramalho and 24 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Valnete das Graças Dantas AndradeLaboratório Central do Estado, Secretaria de Saúde Pública, Belém, PA, Brazil.
Talita Émile Ribeiro AdelinoFundação Ezequiel Dias, Belo Horizonte, MG, Brazil.
Vagner FonsecaDepartamento de Ciências Exatas e da Terra, Universidade do Estado da Bahia, Salvador, BA, Brazil.ORCID 0000-0001-5521-6448
Keldenn Melo Farias MorenoInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.
Luiz Marcelo Ribeiro ToméFundação Ezequiel Dias, Belo Horizonte, MG, Brazil.
Luiz Augusto PereiraLaboratório Central de Saúde Pública Dr Giovanni Cysneiros, Goiânia, GO, Brazil.
Debora Glenda Lima de La-RoqueHemocentro de Ribeirão Preto, Ribeirão Preto, SP, Brazil.
Ana Maria Bispo de FilippisLaboratório de Arbovírus e Vírus Hemorrágicos, Instituto Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
Daniel Garkauskas RamosCoordenacao-Geral de Vigilância de Arboviroses, Brazilian Ministry of Health, Brazil.
Dario Brock RamalhoForça Nacional do SUS, Ministerio da Saude, Brasilia, Federal District, Brazil.
Kátia Cristina de Lima FurtadoSeção de Biologia Molecular I, Laboratório Central do Estado, Secretaria de Saúde Pública, Ministério da Saúde, Belém, PA, Brazil.
Gleissy Adriane Lima BorgesSeção de Biologia Molecular I, Laboratório Central do Estado, Secretaria de Saúde Pública, Ministério da Saúde, Belém, PA, Brazil.
Livia Caricio MartinsEvandro Chagas Institute, Para, Brazil.
Livia C V FrutuosoCoordenacao-Geral de Vigilância de Arboviroses, Brazilian Ministry of Health, Brazil.
Ludmila Oliveira LamounierFundação Ezequiel Dias, Belo Horizonte, MG, Brazil.
Natália Rocha GuimarãesFundação Ezequiel Dias, Belo Horizonte, MG, Brazil.
Patrícia Miriam Sayuri Sato BarrosDivisão de Biologia Médica, Laboratório Central do Estado, Secretaria de Saúde Pública, Belém, PA, Brazil.
Priscila Souza de AlmeidaFundação Ezequiel Dias, Belo Horizonte, MG, Brazil.
Paulo Eduardo de Souza da SilvaInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.
Rodrigo Giesbrecht PinheiroCoordenacao-Geral de Vigilância de Arboviroses, Brazilian Ministry of Health, Brazil.
Rodrigo Guerino StabeliForça Nacional do SUS, Ministerio da Saude, Brasilia, Federal District, Brazil.
Shirley Moreira da Silva ChagasSeção de Biologia Molecular I, Laboratório Central do Estado, Secretaria de Saúde Pública, Ministério da Saúde, Belém, PA, Brazil.
Sílvia Helena Sousa Pietra PedrosoFundação Ezequiel Dias, Belo Horizonte, MG, Brazil.
Simone KashimaHemocentro de Ribeirão Preto, Ribeirão Preto, SP, Brazil.
Solange Gonçalves PenanteSeção de Biologia Molecular I, Laboratório Central do Estado, Secretaria de Saúde Pública, Ministério da Saúde, Belém, PA, Brazil.
Marília Santini de OliveiraCoordenacao-Geral de Laboratórios de Saúde Pública, Brazilian Ministry of Health, Brazil.
Vinicius Lemes da SilvaLaboratório Central de Saúde Pública Dr Giovanni Cysneiros, Goiânia, GO, Brazil.
Wesley C Van VoorhisCenter for Emerging and Re-emerging Infectious Diseases (CERID), Department of Medicine, Division of Allergy & Infectious Diseases, University of Washington, Seattle, WA USA.
Edward C HolmesSchool of Medical Sciences, University of Sydney, Sydney, NSW, Australia.
José LourençoBioISI (Biosystems and Integrative Sciences Institute), University of Lisbon, Lisbon, Portugal; Universidade Católica Portuguesa, Biomedical Research Center, Lisboa, Portugal.
Felipe Campos de Melo IaniFundação Ezequiel Dias, Belo Horizonte, MG, Brazil.
Alberto Simões Jorge JúniorLaboratório Central do Estado, Secretaria de Saúde Pública, Belém, PA, Brazil.
Marta GiovanettiSciences and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, Italy, 00128.
Luiz Carlos Junior AlcantaraInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.

Funding

University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
NIAID NIH HHS U01 AI151698
6 · The paper itself

Abstract

Yellow Fever virus (YFV) continues to challenge public health systems across the Americas, despite decades of successful control and the availability of a highly effective vaccine. Following major outbreaks between 2016 and 2022, YFV re-emerged in Brazil in 2023, with a confirmed infection in a non-human primate in São Paulo linked to viral strains circulating in the Midwest region. This reintroduction, combined with increased YFV activity reported across the Americas, signals an ongoing risk of viral persistence and geographic expansion. In this study, we investigate recent YFV dynamics in forest and peri-urban settings, integrating genomic evidence with ecological and spatial data to trace transmission pathways and assess the potential for urban re-emergence. Our findings highlight the need for sustained surveillance in both sylvatic and transitional zones, especially amid fluctuating vaccine coverage and environmental changes that may facilitate spillover events.

Indexed as

Brazilgenomic surveillancere-emergenceSylvatic transmissionYellow fever virus (YFV)

Identifiers

PMID40297427
PMCPMC12036419

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.