Evidence map›Paper›PMID 40297274›Full record

ArticleOxford medical case reports2025

Kounis syndrome: acute myocardial injury triggered by ant bite-induced anaphylaxis.

Omar Altermanini, Anas A Ashour, Waleed K Abdullatef, Abdulrahman Arabi, Mhd Baraa Habib

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Omar AltermaniniCollege of Medicine, QU Health, Qatar University, P.O. Box 2713, Doha, Qatar.
Anas A AshourInternal medicine department, Hamad medical corporation, P.O. Box 3050, Doha, Qatar.ORCID https://orcid.org/0000-0002-9607-4009
Waleed K AbdullatefCardiology department, Heart hospital, Hamad medical corporation, P.O. Box 3050, Doha, Qatar.
Abdulrahman ArabiCardiology department, Heart hospital, Hamad medical corporation, P.O. Box 3050, Doha, Qatar.
Mhd Baraa HabibCardiology department, Heart hospital, Hamad medical corporation, P.O. Box 3050, Doha, Qatar.ORCID https://orcid.org/0000-0003-4585-2883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaphylaxis triggered by insect bites is well-documented, but its association with acute myocardial injury (AMI) is rare. We report a case of Kounis syndrome, where an ant bite induced anaphylaxis and myocardial injury. A 47-year-old diabetic male presented with anaphylaxis following an ant bite, exhibiting hypotension, respiratory distress, and wheezing. Electrocardiography revealed transient widespread ST depression and ST elevation in lead aVR, a pattern reflecting global ischemia, which is uncommon in Kounis syndrome. Treatment with intramuscular adrenaline stabilized his condition. Peak troponin T levels were 1306 ng/l. Coronary angiography and cardiac MRI were unremarkable, ruling out significant coronary artery disease. The patient was diagnosed with Kounis syndrome and discharged with an EpiPen and instructions for anaphylaxis management. This case highlights the potential for ant bites to trigger anaphylaxis-associated myocardial injury, emphasizing the importance of prompt diagnosis and management of Kounis syndrome in similar scenarios.

Indexed as

acute myocardial injuryanaphylaxisant biteKounis syndrome

Identifiers

PMID40297274
PMCPMC12035684

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