ReviewArthroscopy, sports medicine, and rehabilitation2025
Patient Age and Activity Level, Posterior Tibial Slope, and Use of Allograft Are Significant Risk Factors for Anterior Cruciate Ligament Reconstruction Failure: A Systematic Review.
Review in Arthroscopy, sports medicine, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Role of Allografts in Revision ACL Reconstruction.Medicina (Kaunas, Lithuania) · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To assess the consistency of risk factor reporting for anterior cruciate ligament reconstruction (ACLR) failure after primary reconstruction, identify risk factors more frequently associated with ACLR failure, and help clinicians prevent reinjury in patients with risk factors for ACLR failure. Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were used to conduct a systematic review. Initial title and abstract screening yielded 561 studies, from which 76 studies were assessed for eligibility. Thirty-two full-text studies met the following inclusion criteria: (1) clinical studies of anterior cruciate ligament injuries; (2) patients undergoing ACLR; (3) clinical outcome data, including failure rate; (4) studies assessing preoperative risk factors for failure; and (5) manuscripts published within the past 6 years. These studies were subdivided into those that defined ACLR failure as revision surgery or graft failure. Results: Ten risk factors were included in the review for 22 studies defining ACLR failure as revision surgery. Eight risk factors were included in the review for 10 studies defining ACLR failure as graft failure. Posterior tibial slope (PTS) (80%, 4/5 studies), age (79%, 11/14 studies), and graft characteristics (71%, 5/7 studies) such as allograft versus bone-patellar tendon-bone autograft, high-dose radiation, and BioCleanse preparation technique were the most significant risk factors for revision ACLR. PTS (100%, 2/2 studies) and activity level (67%, 2/3 studies) were the most significant risk factors for graft failure. Conclusions: Age, PTS, use of allograft, and activity level are significant preoperative risk factors that should be considered when attempting to prevent reinjury in ACLR candidates. Studies investigating risk factors for ACLR failure often fail to control for confounding variables that can influence outcomes. Level of Evidence: Level IV, systematic review of Level II to IV studies.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.