ArticleCureus2025
Skin-Reducing Mastectomy and Direct-to-Implant Breast Reconstruction Without Mesh: A Single-Institute Experience.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Prepectoral versus Retropectoral Direct to Implant Breast Reconstruction after Skin-reducing Mastectomy: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2026Article
- Patient-reported outcomes following various incision techniques in breast reconstruction: an observational cohort study in China.Journal of cancer research and clinical oncology · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPerforming breast reconstruction in large and ptotic breasts remains technically challenging, with a high incidence of postoperative complications and unsatisfactory cosmetic results. Skin-reducing mastectomy (SRM) was introduced for breast reconstruction for females with macromastia. In this study, we report the experience in Alexandria Main University Hospital (AMUH), Alexandria, Egypt, with SRM and direct-to-implant (DTI) breast reconstruction without the utilization of biological or synthetic meshes. PATIENTS AND
methodsA prospective study was carried out at AMUH from October 2020 to October 2022. It included 20 female patients having large and ptotic breasts who were indicated for mastectomy, with the exclusion of non-motivated patients, inflammatory breast cancer, significant clinical comorbidities, and patients indicated for postoperative radiotherapy. All the operations were done as a single stage in which the SRM was performed through a Wise-pattern skin incision, along with the creation of a dermal sling to cover the implant.
resultsA total of 20 surgeries were performed, in which the implant was placed in a pre-pectoral position in 10 cases. In the other 10 cases, the implant was inserted partially subpectoral by creating a musculo-dermal pouch to envelop the implant. The most prevalent complication encountered was delayed wound healing at the area of the inverted T-junction. None of the studied patients experienced wound infection, capsular contracture, or implant loss.
conclusionSRM and DTI breast reconstruction is a feasible technique that can be safely used in patients with large and ptotic breasts. The inferior dermal sling allows for a single-stage implant-based breast reconstruction without the utilization of biological or synthetic meshes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.