Evidence map›Paper›PMID 40296914›Full record

ReviewOncology research2025

Current innovations in head and neck cancer: From diagnostics to therapeutics.

Tayyaba Sattar, Iqra Nazir, Mehreen Jabbar, Javaria Malik, Saba Afzal, Sana Hanif, Seyed Ali Mosaddad, Ahmed Hussain, Hamid Tebyaniyan

Abstract readReview
In one paragraph

Review in Oncology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tayyaba SattarUniversity Institute of Physical Therapy, The University of Lahore, Lahore, 54000, Pakistan.
Iqra NazirUniversity Institute of Physical Therapy, The University of Lahore, Lahore, 54000, Pakistan.
Mehreen JabbarUniversity Institute of Physical Therapy, The University of Lahore, Lahore, 54000, Pakistan.
Javaria MalikUniversity Institute of Physical Therapy, The University of Lahore, Lahore, 54000, Pakistan.
Saba AfzalUniversity Institute of Physical Therapy, The University of Lahore, Lahore, 54000, Pakistan.
Sana HanifFaculty of Pharmacy, The University of Lahore, Lahore, 54770, Pakistan.
Seyed Ali MosaddadDepartment of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, India.
Ahmed HussainSchool of Dentistry, Edmonton Clinic Health Academy, University of Alberta, Alberta, T6G 1C9, Canada.
Hamid TebyaniyanFaculty of Pharmacy, The University of Lahore, Lahore, 54770, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Head and neck cancers (HNC) account for a significant global health burden, with increasing incidence rates and complex treatment requirements. Traditional diagnostic and therapeutic approaches, while effective, often result in substantial morbidity and limitations in personalized care. This review provides a comprehensive overview of the latest innovations in diagnostics and therapeutic strategies for HNC from 2015 to 2024. Methods: A review of literature focused on pe-reviewed journals, clinical trial databases, and oncology conference proceedings. Key areas include molecular diagnostics, imaging technologies, minimally invasive surgeries, and innovative therapeutic strategies. Results: Technologies like liquid biopsy next-generation sequencing (NGS) have greatly improved diagnostic accuracy and personalization in HNC care. These advancements have improved survival rates and enhanced patients' quality of life. Personalized therapeutic approaches, including immune checkpoint inhibitors, precision radiation therapy, and surgery, have led to enhanced treatment efficacy while reducing side effects. The integration of AI and machine learning into diagnostics and treatment planning shows promise in optimizing clinical decision-making and predicting treatment outcomes. Conclusion: The current innovations in diagnostics and therapeutics are reshaping the management of head and neck cancer, offering more tailored and effective approaches to care. Overall, the continuous integration of these innovations in clinical practice is reshaping HNC treatment and improving patient outcomes and survival rates. Future research should focus on further refining these technologies, addressing challenges related to accessibility, and exploring their long-term clinical benefits in diverse patient populations.

Indexed as

Head and Neck NeoplasmsBiomarkers, TumorHigh-Throughput Nucleotide SequencingHumansPrecision MedicineBiomarkers, TumorDiagnosticsHead and neck cancer (HNC)InnovationsTherapeutics

Identifiers

PMID40296914
PMCPMC12034008

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.