Evidence map›Paper›PMID 40296877›Full record

ArticleBladder cancer (Amsterdam, Netherlands)

Higher resilience in radical cystectomy patients is associated with improved health related quality of life post-operatively.

Lauren N Kennedy, Caleb S Miller, Danica N May, Evan Fruhauf, Hadley W Wyre, Moben Mirza, Junqiang Dai, Jeffrey M Holzbeierlein, Hayley Stolzle, Moira Mulhern and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Bladder cancer (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06337305 (Resiliency in Patients Undergoing Radical Cystectomy for Bladder Cancer), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06337305 completednot on this map

Resiliency in Patients Undergoing Radical Cystectomy for Bladder Cancer

TypeobservationalSponsorUniversity of Kansas Medical CenterRan2020 to 2023Enrolled74ConditionsBladder Cancer
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Postoperative pain and surgical recovery: are we treating pain or building resilience?Frontiers in pain research (Lausanne, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lauren N KennedyDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.
Caleb S MillerDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.
Danica N MayDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.
Evan FruhaufDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.
Hadley W WyreDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.
Moben MirzaDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.
Junqiang DaiDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.
Jeffrey M HolzbeierleinDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.
Hayley StolzleUniversity of Kansas Medical Center, Turning Point, Kansas City, KS, USA.
Moira MulhernUniversity of Kansas Medical Center, Turning Point, Kansas City, KS, USA.
Mihaela E SardiuDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.
Eugene K LeeDepartment of Urology, University of Kansas Medical Center, Kansas City, KS, USA.ORCID https://orcid.org/0000-0002-0457-2917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Radical cystectomy (RC) with urinary diversion (UD) is associated with substantial morbidity. Enhanced recovery after surgery protocols, increased robotic usage, and improvements in urinary diversion have been evaluated for their effects on health-related Quality of Life (HRQoL), however, results are mixed. How psychosocial traits inherent to the patient influence HRQoL outcomes is unknown in this population. Objective: This study aimed to evaluate resilience and its correlation with HRQoL in a cohort of patients undergoing RC for bladder cancer. Methods: Patients with bladder cancer undergoing RC with UD at the University of Kansas Medical Center were screened for prospective enrollment in this clinical trial (NCT06337305). The validated Connor-Davidson Resilience Scale 25 (CD-RISC), the Functional Assessment of Cancer Therapy-Bladder-Cystectomy (FACT-BL-Cys), and the PROMIS 29-v2.0 were administered preoperatively, 2-3 weeks postoperatively, and at 90 days postoperatively. Patient demographics, pathology, and complication data were collected. Results: Between November 2020 and August 2022, 52 patients completed the survey data. Patients were stratified based on baseline resilience score. The higher resilience group scored 85.7, 85.0, and 81.9 compared to 64.9, 70.4, and 72.0 at the three time points which all remained statistically significant. Participant resilience scores using the CD-RISC did not correlate with quality-of-life measures using the PROMIS or FACT-Bl-Cys at baseline or two weeks but did correlate at 90 days (p < 0.01). Resilience did not correlate with the patient's pathology stage or 90-day complication data. Conclusions: Patients with higher baseline resilience maintain higher levels throughout the perioperative period and correlate with QOL.

Indexed as

cystectomyhealth related quality of lifePROMsresilience

Identifiers

PMID40296877
PMCPMC12033614

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.