Evidence map›Paper›PMID 40296387›Full record

ArticleLung India : official organ of Indian Chest Society2025

Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity.

Kyriaki Cholidou, Nektarios Anagnostopoulos, Konstantinos Bartziokas, Konstantinos Vafeiadis, Agamemnon Bakakos, Aggelos Vontetsianos, Vasiliki Gogou, Zoi Sotiropoulou, Christina Anagnostopoulou, Anna Papasarantou and 3 more

Abstract read
In one paragraph

Article in Lung India : official organ of Indian Chest Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Kyriaki Cholidou1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Nektarios Anagnostopoulos1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Konstantinos BartziokasPrivate Sector, Trikala, Greece.
Konstantinos Vafeiadis1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Agamemnon Bakakos1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Aggelos Vontetsianos1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Vasiliki Gogou1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Zoi Sotiropoulou1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Christina Anagnostopoulou1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Anna Papasarantou1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Paschalis SteiropoulosDepartment of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Petros Bakakos1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.
Andriana I Papaioannou1 Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, Sotiria Chest Diseases Hospital, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMean platelet volume (MPV) and red blood cll distribution width (RDW) have been assosiated with sleep apnea syndrome severity.

objectiveTo investigate the correlation of mean platelet volume and red blood cell distribution width with obesity sleep apnoea syndrome (OSAS) severity.

methodsNinety patients underwent PSG. Patients with an apnoea-hypopnoea index (AHI) <5 were used as controls. Patients with AHI >5 were divided into mild: 5 ≤ AHI <15, moderate: 15≤ AHI <30 and severe OSAS: AHI ≥30. Patients >65 years, with body mass index (BMI) >40, central sleep apnoea syndrome, cardiovascular or other significant comorbidities were excluded. Blood sample collection occurred one day before polysomnography (PSG).

resultsSixty-four patients were included in our study. Fifty-seven (89.1%) had OSAS (16% mild, 25% moderate and 48.4% severe) while the remaining 7 (10.1%) were used as controls. MPV was similar among groups [8.1 (7.1, 9.2) vs 7.9 (6.8, 10.1) vs 8.5 (7.4, 9.1) vs 8.4 (7.6, 9.7), P = .930 for control, mild, moderate and severe OSAS, respectively]. RDW did not differ between OSAS patients and control [median (IQR) 14.4 (13.4, 15.3) vs 14.0 (13.5, 16.7), P = .950], while there was no significant difference among different stages of OSAS severity [14.0 (13.5, 16.7) vs 13.9 (11.4, 14.8) vs 14.4 (14.0, 15.3) vs 14.4 (13.3, 15.6), P = .517] for control, mild, moderate and severe OSAS, respectively.

conclusionOSAS patients have elevated levels of RDW and MPV compared to controls; however, there was no association between OSAS severity and MPV or RDW.

Indexed as

Biomarkersmean platelet volumeobstructive sleep apnoea syndromered blood cell distribution widthseverity

Identifiers

PMID40296387
PMCPMC12097666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.