Evidence map›Paper›PMID 40296286›Full record

ArticleAnnals of hepato-biliary-pancreatic surgery2025

Safety and efficacy of minimally invasive splenectomy with endotherapy for non-cirrhotic portal fibrosis: A retrospective cohort study.

Lokesh Agarwal, Sanjamjot Singh, Vaibhav Kumar Varshney, Subhash Chandra Soni, B Selvakumar, Peeyush Varshney, Shaikh Muna Afroz, Tashmeen Kaur Sethi, Binit Sureka

Abstract read
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In one paragraph

Article in Annals of hepato-biliary-pancreatic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lokesh AgarwalDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0002-7731-3908
Sanjamjot SinghDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0001-5857-155X
Vaibhav Kumar VarshneyDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0003-1771-2787
Subhash Chandra SoniDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0001-9972-8920
B SelvakumarDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0002-2280-3862
Peeyush VarshneyDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0001-6276-1890
Shaikh Muna AfrozDepartment of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0001-7494-2189
Tashmeen Kaur SethiDepartment of Radiodiagnosis, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0009-0001-8672-5533
Binit SurekaDepartment of Radiodiagnosis, All India Institute of Medical Sciences, Jodhpur, India.ORCID https://orcid.org/0000-0001-7200-296X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-cirrhotic portal fibrosis (NCPF), a leading cause of non-cirrhotic portal hypertension (NCPH), commonly presents with splenomegaly, esophageal varices, and preserved liver function. While minimally invasive splenectomy (MIS) offers advantages over open splenectomy, concerns persist due to the risks associated with portal hypertension. This study evaluates the feasibility, safety, and long-term outcomes of MIS in non-bleeder NCPF patients, highlighting perioperative challenges and techniques. Thirteen consecutive non-bleeder NCPF patients undergoing MIS between November 2017 and December 2023 were analyzed. Procedures included eight laparoscopic and four robotic splenectomies, with one conversion to open surgery. Additionally, two patients underwent laparoscopic and one robotic gastric devascularization. Perioperative parameters such as operative time, blood loss, hospital stay, and complications were recorded. The median operative time was 240 minutes, and median blood loss was 150 mL. One patient required transfusion, and one developed splanchnic venous thrombosis, managed conservatively. Median hospital stay was three days, with no 90-day mortality. Follow-up assessments included clinical evaluation, blood tests, Doppler ultrasound of the splenoportal axis, and upper gastrointestinal endoscopy. At a median follow-up of 16 months (interquartile range 12-43), significant improvements were observed in hemoglobin, leukocyte, and platelet counts (

Indexed as

Laparoscopic surgeryMinimally invasive splenectomyNon-cirrhotic portal fibrosisNon-cirrhotic portal hypertensionRobotic surgery

Identifiers

PMID40296286
PMCPMC12377979

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.