Cerium-doped calcium carbonate microparticles combined with low-intensity ultrasound for efficient sonodynamic therapy in body sculpting.

Jhih-Ni Lin, Chih-Ying Chi, Yu-Ying Lin, Che-Yung Kuan, Chia-Tien Chang, Li-Ze Lin, I-Hsuan Yang, Feng-Huei Lin

Abstract read

In one paragraph

Article in Journal of biological engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jhih-Ni LinInstitute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, 106319, Taiwan.

Chih-Ying ChiCardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan.

Yu-Ying LinInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli County, Zhunan, 350401, Taiwan.

Che-Yung KuanInstitute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, 106319, Taiwan.

Chia-Tien ChangInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli County, Zhunan, 350401, Taiwan.

Li-Ze LinDepartment of Materials Science and Engineering, National United University, Miaoli County, Miaoli City, 360301, Taiwan.

I-Hsuan Yang *Department of Biomedical Science and Technology, National Sun Yat-sen University, No. 70, Lien-hai Rd, Kaohsiung, 804201, Taiwan. ihyang@mail.nsysu.edu.tw.

Feng-Huei Lin *Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, 106319, Taiwan. double@ntu.edu.tw.

Funding

National Health Research Institutes BN-112-PP-01, BN-113-PP-01, and BN-113-GP-09

6 · The paper itself

Abstract

Excessive caloric intake and reduced energy expenditure contribute to obesity and localized fat accumulation, adversely affecting overall health. Despite advancements in obesity treatments, noninvasive approaches for targeted fat reduction remain limited. This study introduces a novel sonosensitizer microparticle, cerium-doped calcium carbonate (CaCO

Indexed as

Body sculptureCalcium carbonateCeriumLow-intensity ultrasoundReactive oxygen species

Identifiers

PMID40296005

DOI10.1186/s13036-025-00505-z

PMCPMC12036128

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.