Evidence map›Paper›PMID 40295935›Full record

ArticleBMC pregnancy and childbirth2025

Impact of the COVID-19 pandemic on parvovirus B19 infection rates in pregnancy: is there a post-pandemic epidemic?

Christina Haberl, Nawa Schirwani-Hartl, Pilar Palmrich, Valentina Oblin, Florian Heinzl, Nicole Perkmann-Nagele, Julia Binder

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christina HaberlDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Nawa Schirwani-HartlDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Pilar PalmrichDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Valentina OblinDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Florian HeinzlDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Nicole Perkmann-NageleDepartment of Laboratory Medicine, Division of Clinical Virology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Julia BinderDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. julia.binder@meduniwien.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesImplemented public health measures to avoid the spread of SARS-CoV-2, influenced the circulation of various viral infections including parvovirus B19. Notably, pregnancies affected by parvovirus B19 have a high risk for severe fetal anemia and fetal demise. This study evaluates changes in parvovirus infection rates after the SARS-CoV-2 pandemic.

methodsThis was a retrospective cohort-study assessing the prevalence of parvovirus B19 among pregnant women at a tertiary referral center in Austria from January 2013 to December 2023 with particular interest in the influence of the COVID-19 pandemic on infection rates of parvovirus B19. Women who had PCR testing for parvovirus due to suspicion of infection were included in this study. To compare infection rates before, during, and after the pandemic, three study groups were defined in concordance with Austrian public health measures: A pre-pandemic group (Group 1) including all pregnant women who tested for parvovirus B19 from January 2013 to the beginning of the COVID-19 lockdown in March 2020, a pandemic group (Group 2) including all patients who had PCR testing during the COVID-19 lockdown and a post-pandemic group (Group 3) including all patients who had PCR testing from the end of the pandemic in April 2023 to December 2023.

resultsA total of 251 pregnant women who had PCR testing for parvovirus B19 during the study period were identified, including 27 women with a positive test result. In the pre-pandemic group (n = 141) 14 women had a positive test result, in the pandemic group (n = 83) 3 women tested positive and in the post-pandemic group (n = 27) 10 women tested positive. The overall prevalence of parvovirus B19 was 0.108, and annually, it varies from 0.000 in 2021 to 0.355 in 2023. Considering the predefined study groups, the highest prevalence was demonstrated in the post-pandemic group (0.370), whereas the lowest was in the pandemic group (0.036). In the pre-pandemic group, the prevalence was 0.099. Prevalence of the predefined study groups differed significantly (p ≤ 0.001).

conclusionThis study demonstrates a significant rise of parvovirus B19 infections among pregnant women after the COVID-19 pandemic indicating a major impact of the pandemic and associated public health measures on parvovirus B19 infection rates.

Indexed as

COVID-19Parvoviridae InfectionsParvovirus B19, HumanPregnancy Complications, InfectiousAdultAustriaFemaleHumansPandemicsPregnancyPrevalenceRetrospective StudiesSARS-CoV-2Young AdultCoronavirusCOVID-19Infections in pregnancyParvovirusSARS-CoV-2

Identifiers

PMID40295935
PMCPMC12038933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.