Evidence map›Paper›PMID 40295767›Full record

ReviewNpj viruses2024

Renewed insights into Ackermannviridae phage biology and applications.

Anders Nørgaard Sørensen, Lone Brøndsted

Abstract readReview
In one paragraph

Review in Npj viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Isolation and Characterization of aAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genomic characterization of fourFood science and biotechnology · 2025
    Article
  8. Treatment ofViruses · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anders Nørgaard SørensenDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Lone BrøndstedDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg C, Denmark. lobr@sund.ku.dk.

Funding

Danmarks Frie Forskningsfond 9041-00159B
6 · The paper itself

Abstract

The Ackermannviridae family was established in 2017, containing phages previously classified within the Myoviridae family under the Viunalikevirus genus. Ackermannviridae phages have been increasingly studied due to their broad range of hosts among Enterobacteriaceae, and currently, 174 complete genomes are available on NCBI. Instrumental for their wide host infectivity, Ackermannviridae phages display a branched complex of multiple Tail Spike Proteins (TSPs). These TSPs recognize diverse surface polysaccharide receptors, allowing the phages to target strains with distinct lipopolysaccharides or capsular polysaccharides. This review gives an updated overview of the taxonomy and hosts of the expanding Ackermannviridae family with significant emphasis on recent advances in structural and computational biology for elucidating TSP diversity, structural domains, and assembly of the branched TSP complex. Furthermore, we explore the potential of engineering Ackermannviridae phages and discuss the challenges of using transducing wildtype phages for biocontrol. Finally, this review identifies bottlenecks hindering further advances in understanding Ackermannviridae phage biology and applications.

Identifiers

PMID40295767
PMCPMC11721090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.