Evidence map›Paper›PMID 40295766›Full record

ArticleNpj viruses2024

Influenza B viruses are more susceptible to high temperatures than influenza A viruses.

Kosuke Takada, Yurie Kida, Shinji Watanabe, Tokiko Watanabe

Abstract read
In one paragraph

Article in Npj viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. medRxiv : the preprint server for health sciences · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kosuke TakadaDepartment of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Yurie KidaDepartment of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Shinji WatanabeResearch Center for Influenza and Respiratory Viruses, National Institute of Infectious Diseases, Musashimurayama, Tokyo, Japan.
Tokiko WatanabeDepartment of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan. tokikow@biken.osaka-u.ac.jp.

Funding

Japan Agency for Medical Research and Development JP19fk0108113Japan Society for the Promotion of Science JP22H02521
6 · The paper itself

Abstract

Seasonal influenza is caused by two subtypes of influenza A virus (A/H1N1 and A/H3N2) and two lineages of influenza B viruses (B/Victoria-lineage and B/Yamagata-lineage). Seasonal influenza viruses replicate efficiently in the human upper respiratory tract, where the temperature is 33 °C. In this study, we investigated the susceptibility of seasonal influenza A and B viruses to different temperatures. We examined the differences in viral replication efficiency inside cultured cells and in infectious titre outside cultured cells at different temperatures (i.e., 33 °C, 37 °C, and 39 °C). We found that there were differences in temperature sensitivity between influenza A and B viruses, with influenza B viruses being more temperature sensitive. In addition, we found that cells cultured at 39 °C and infected with influenza B virus showed decreased expression of HA protein with receptor-binding activity on the cell surface. Our findings contribute to our understanding of the properties of seasonal influenza viruses.

Identifiers

PMID40295766
PMCPMC11721434

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.